UniProt Accession

 ARPC2_DROME; Q9VIM5; Q95T07 

Genbank Protein ID

 AE014134; AY060391 

Genbank Nucleotide ID

 AAF53892.2; AAL25430.1 

Protein Name

 Probable actin-related protein 2/3 complex subunit 2 

Protein Synonyms/Alias

 Arp2/3 complex 34 kDa subunit; p34-ARC 

Gene Name

 Arc-p34 

Gene Synonyms/Alias

 CG10954 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
27	RNAQAGLKPESIDIR	acetylation	[1]
275	AKTSDFLKVLNRARP	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). 

Sequence Annotation

  

Keyword

 Actin-binding; Complete proteome; Cytoplasm; Cytoskeleton; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 301 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
 GO:0003779; F:actin binding; ISS:FlyBase.
 GO:0000902; P:cell morphogenesis; IMP:FlyBase.
 GO:0030031; P:cell projection assembly; IMP:FlyBase.
 GO:0030866; P:cortical actin cytoskeleton organization; IMP:FlyBase.
 GO:0046331; P:lateral inhibition; IMP:FlyBase.
 GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
 GO:0008360; P:regulation of cell shape; IMP:FlyBase. 

Interpro

 IPR007188; P34-arc. 

Pfam

 PF04045; P34-Arc 

SMART

  

PROSITE

  

PRINTS