UniProt Accession

 C9J826_HUMAN; C9J826 

Genbank Protein ID

 AC109319; AC130686 

Genbank Nucleotide ID

  

Protein Name

 Junction plakoglobin 

Protein Synonyms/Alias

  

Gene Name

 JUP 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
40	CVPSVSSKGIMEEDE	ubiquitination	[1]
124	AEPSQLLKSAIVHLI	ubiquitination	[1, 2]
149	RALPELTKLLNDEDP	ubiquitination	[1, 2]
161	EDPVVVTKAAMIVNQ	ubiquitination	[1, 2, 3]
224	EGLLAIFKSGGIPAL	ubiquitination	[1, 3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 277 AA 

Protein Sequence

Gene Ontology

 GO:0016327; C:apicolateral plasma membrane; IEA:Compara.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0030057; C:desmosome; IEA:Compara.
 GO:0005916; C:fascia adherens; IEA:Compara.
 GO:0005882; C:intermediate filament; IEA:Compara.
 GO:0009898; C:internal side of plasma membrane; IEA:Compara.
 GO:0016328; C:lateral plasma membrane; IEA:Compara.
 GO:0030018; C:Z disc; IEA:Compara.
 GO:0005198; F:structural molecule activity; IEA:Compara.
 GO:0016337; P:cell-cell adhesion; IEA:Compara.
 GO:0002159; P:desmosome assembly; IEA:Compara.
 GO:0051291; P:protein heterooligomerization; IEA:Compara.
 GO:0043588; P:skin development; IEA:Compara. 

Interpro

 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR000225; Armadillo.
 IPR013284; Beta-catenin. 

Pfam

 PF00514; Arm 

SMART

 SM00185; ARM 

PROSITE

 PS50176; ARM_REPEAT 

PRINTS

 PR01869; BCATNINFAMLY.