| Tag | Content |
|---|
| CPLM ID | CPLM-009129 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Anthrax toxin receptor 2 |
Protein Synonyms/Alias | Capillary morphogenesis gene 2 protein; CMG-2 |
Gene Name | ANTXR2 |
Gene Synonyms/Alias | CMG2 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 268 | EEEPLPTKKWPTVDA | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Necessary for cellular interactions with laminin and the extracellular matrix. |
Sequence Annotation | DOMAIN 44 213 VWFA.
METAL 52 52 Divalent metal cation.
METAL 54 54 Divalent metal cation.
METAL 118 118 Divalent metal cation.
MOD_RES 147 147 Phosphothreonine.
CARBOHYD 250 250 N-linked (GlcNAc...) (Potential).
CARBOHYD 260 260 N-linked (GlcNAc...) (Potential).
DISULFID 39 218 |
Keyword | 3D-structure; Alternative splicing; Cell membrane; Complete proteome; Disease mutation; Disulfide bond; Endoplasmic reticulum; Glycoprotein; Membrane; Metal-binding; Phosphoprotein; Polymorphism; Receptor; Reference proteome; Secreted; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 489 AA |
Protein Sequence | MVAERSPARS PGSWLFPGLW LLVLSGPGGL LRAQEQPSCR RAFDLYFVLD KSGSVANNWI 60
EIYNFVQQLA ERFVSPEMRL SFIVFSSQAT IILPLTGDRG KISKGLEDLK RVSPVGETYI 120
HEGLKLANEQ IQKAGGLKTS SIIIALTDGK LDGLVPSYAE KEAKISRSLG ASVYCVGVLD 180
FEQAQLERIA DSKEQVFPVK GGFQALKGII NSSNGIAAII VILVLLLLLG IGLMWWFWPL 240
CCKVVIKDPP PPPAPAPKEE EEEPLPTKKW PTVDASYYGG RGVGGIKRME VRWGDKGSTE 300
EGARLEKAKN AVVKIPEETE EPIRPRPPRP KPTHQPPQTK WYTPIKGRLD ALWALLRRQY 360
DRVSLMRPQE GDEVCIWECI EKELTA 386 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0004872; F:receptor activity; IEA:InterPro. GO:0022414; P:reproductive process; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |