CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031064
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 EH domain-containing protein 2 
Protein Synonyms/Alias
 cDNA FLJ55555, highly similar to EH-domain-containing protein 2 
Gene Name
 EHD2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
180YIISYLKKEMPSVFGmethylation[1]
188EMPSVFGKENKKKQLmethylation[1]
191SVFGKENKKKQLILKmethylation[1]
Reference
 [1] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 407 AA 
Protein Sequence
MCAQLPNQVL ESISIIDTPG ILSGAKQRVS RGYDFPAVLR WFAERVDLII LLFDAHKLEI 60
SDEFSEAIGA LRGHEDKIRV VLNKADMVET QQLMRVYGAL MWALGKVVGT PEVLRVYIGS 120
FWSQPLLVPD NRRLFELEEQ DLFRDIQGLP RHAALRKLND LVKRARLVRV HAYIISYLKK 180
EMPSVFGKEN KKKQLILKLP VIFAKIQLEH HISPGDFPDC QKMQELLMAH DFTKFHSLKP 240
KLLEALDEML THDIAKLMPL LRQEELESTE VGVQGGAFEG THMGPFVERG PDEAMEDGEE 300
GSDDEAEWVV TKDKSKYDEI FYNLAPADGK LSGSKAKTWM VGTKLPNSVL GRIWKLSDVD 360
RDGMLDDEEF ALASHLIEAK LEGHGLPANL PRRLVPPSKR RHKGSAE 407 
Gene Ontology
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0030866; P:cortical actin cytoskeleton organization; IEA:Compara.
 GO:0006897; P:endocytosis; IEA:Compara.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR001401; Dynamin_GTPase.
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR000261; EPS15_homology.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00350; Dynamin_N 
SMART
 SM00027; EH 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS50031; EH 
PRINTS