| Tag | Content |
|---|
| CPLM ID | CPLM-006597 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Formation of crista junctions protein 1 |
Protein Synonyms/Alias | Altered inheritance of mitochondria protein 28; Found in mitochondrial proteome protein 13; Mitofilin |
Gene Name | FCJ1 |
Gene Synonyms/Alias | AIM28; FMP13; YKR016W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 369 | NLLSTFNKKSCCDDG | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Multifunctional regulator of mitochondrial architecture and protein biogenesis. May act in concert with ATP synthase dimers to generate inner membrane structure and consequently normal mitochondrial morphology. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway. |
Sequence Annotation | |
Keyword | Coiled coil; Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 540 AA |
Protein Sequence | MMLRTTASRK IVLRRGLASI NTGTTVASKK ASHKFRNTLW TIALSATAFY AGGIIYSQKN 60
DKFGDFFSNN VPFAEDLLET YEHYHDRPTL FLEDSWDGLK AKSNDLLSGL TGSSQTRRSN 120
RENIEVKKIL SLEPLNIETE NSDPQLKEII GSLNDLINSL NDSNLSIPES EFNSIKKSNQ 180
NMLTNLSQLN ETLKEALSNY MIQRTSEVIT ELNTQYENSK REFEKNLQKN LLQEVDEFKE 240
NLTKQKDKEL EEKLKANEEL LQAKHANEVG LLSITQVKEF NKIIKDKIEK ERNGRLAHLE 300
EINSEVNDLS KSIDRSSKIL SKNEALVQLT FQVDEIKSRI NNNNLPDVNI DKELSRLKLL 360
SNLLSTFNKK SCCDDGDCCS CKKGNKNEGK EGKISCKCKP KTNPPSLLSV ALDELESTCS 420
GKKILSNEQI YNRWNLLADD FKTASLLPPN SGILGQLTAK VFSLFLFTKT GNPSNATDFD 480
SVYARVGDNL RVSNLNDAVE EVVSLKGWPH KVCESWIEDA RRKLEVQRLV EILDCEIRTL 540 |
Gene Ontology | GO:0031305; C:integral to mitochondrial inner membrane; IDA:SGD. GO:0030061; C:mitochondrial crista; IDA:SGD. GO:0044284; C:mitochondrial crista junction; IDA:SGD. GO:0042407; P:cristae formation; IMP:SGD. GO:0045041; P:protein import into mitochondrial intermembrane space; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |