| Tag | Content |
|---|
| CPLM ID | CPLM-016807 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Kelch-like protein 11 |
Protein Synonyms/Alias | |
Gene Name | Klhl11 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 453 | SFGLTEVKGKLYSIG | ubiquitination | [1] | | 455 | GLTEVKGKLYSIGGH | ubiquitination | [1] | | 481 | VYNPELDKWHNLESA | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation (By similarity). |
Sequence Annotation | DOMAIN 95 171 BTB.
DOMAIN 206 308 BACK.
REPEAT 361 408 Kelch 1.
REPEAT 409 454 Kelch 2.
REPEAT 456 502 Kelch 3.
REPEAT 504 557 Kelch 4.
REPEAT 611 662 Kelch 5. |
Keyword | Alternative splicing; Complete proteome; Kelch repeat; Reference proteome; Repeat; Signal; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 709 AA |
Protein Sequence | MAAAVAAAAA AAAAAASFQV LEMESMETAV AGSASLAAEV RGSGTVDFVT GAGISTLVDT 60
GGSDPGPEAE DFECSTHCSE LSWRQNEQRR QGLFCDITLC FGGAGGREFR AHRSVLAAAT 120
EYFTPLLSGQ FSESRSGRVE MRKWSSEPGP EPDTVEAVIE YMYTGRIRVS TGSVHEVLEL 180
ADRFLLIRLK EFCGEFLKKK LHLSNCVAIH SLAHMYTLSQ LALKAADMIR RNFYKVIQDE 240
EFYTLPFHLI RDWLSDLEIT VDSEEVLFET VLKWVQRNAE ERERYFEELF KLLRLSQMKP 300
TYLTRHVKPE RLVANNEVCV KLVAEAVERH ALRAENIQSG TLQQPTSQVS LLPRYGQNMD 360
VIMVIGGVSE GGDYLSECVG YFVDEDRWVN LPHIHNHLDG HAVAITESYV YVAGSMEPGF 420
AKTVERYNPN LNTWEHVCSL MTRKHSFGLT EVKGKLYSIG GHGNFSPGFK DVTVYNPELD 480
KWHNLESAPK ILRDVKALAI EDRFVYIAAR TPVDRDTEDG LKAVITCYDT ETRQWQDVES 540
LPLIDNYCFF QMSVVNSNFY QTASCCPKSY SLENEEAVRK IAGQVSDEIL ESLPPEVLSI 600
EGAAICYYRD DVFIIGGWKN SDDIDKQYRK EAYRYCAERK RWMLLPPMPQ PRCRATACHV 660
RIPYRYLHGT QRYPMPQNLM WQKDRIRQMQ EIHRHALNMR RVPSSQIEC 709 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |