| Tag | Content |
|---|
| CPLM ID | CPLM-005084 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DNA gyrase subunit B |
Protein Synonyms/Alias | |
Gene Name | gyrB |
Gene Synonyms/Alias | MPN_003; MP151 |
Created Date | July 27, 2013 |
Organism | Mycoplasma pneumoniae (strain ATCC 29342 / M129) |
NCBI Taxa ID | 272634 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 308 | GFRNALVKIINRFAV | acetylation | [1] | | 579 | KQQHPNLKYNLQRYK | acetylation | [1] |
|
Reference | [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium. van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC. Mol Syst Biol. 2012 Feb 28;8:571. [ PMID: 22373819] |
Functional Description | DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity). |
Sequence Annotation | DOMAIN 435 549 Toprim.
METAL 441 441 Magnesium 1; catalytic (By similarity).
METAL 514 514 Magnesium 1; catalytic (By similarity).
METAL 514 514 Magnesium 2 (By similarity).
METAL 516 516 Magnesium 2 (By similarity). |
Keyword | ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase; Magnesium; Metal-binding; Nucleotide-binding; Reference proteome; Topoisomerase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 650 AA |
Protein Sequence | MEDNNKTQAY DSSSIKILEG LEAVRKRPGM YIGSTGEEGL HHMIWEIIDN SIDEAMGGFA 60
STVKLTLKDN FVTIVEDDGR GIPVDIHPKT NRSTVETVFT VLHAGGKFDN DSYKVSGGLH 120
GVGASVVNAL SSSFKVWVAR EHQQYFLAFH NGGEVIGDLV NEGKCDKEHG TKVEFVPDFT 180
VMEKSDYKQT VIASRLQQLA FLNKGIQIDF VDERRQNPQS FSWKYDGGLV QYIHHLNNEK 240
EPLFEDIIFG EKTDTVKSVS RDESYTIKVE VAFQYNKTYN QSIFSFCNNI NTTEGGTHVE 300
GFRNALVKII NRFAVENKFL KETDEKITRD DICEGLTAII SIKHPNPQYE GQTKKKLGNT 360
EVRPLVNSIV SEIFERFMLE NPQEANAIIR KTLLAQEARR RSQEARELTR RKSPFDSGSL 420
PGKLADCTTR DPSISELYIV EGDSAGGTAK TGRDRYFQAI LPLRGKILNV EKSHFEQIFN 480
NVEISALVMA VGCGIKPDFE LEKLRYNKII IMTDADVDGA HIRTLLLTFF FRFMYPLVEQ 540
GNIYIAQPPL YKVSYSNKDL YMQTDVQLEE WKQQHPNLKY NLQRYKGLGE MDAIQLWETT 600
MDPKVRTLLK VTVEDASIAD KAFSLLMGDE VPPRREFIEQ NARNVKNIDI 650 |
Gene Ontology | GO:0005694; C:chromosome; IEA:InterPro. GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:HAMAP. GO:0003918; F:DNA topoisomerase type II (ATP-hydrolyzing) activity; IEA:HAMAP. GO:0000287; F:magnesium ion binding; IEA:HAMAP. GO:0006265; P:DNA topological change; IEA:InterPro. GO:0006261; P:DNA-dependent DNA replication; IEA:HAMAP. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |