UniProt Accession

 CH10_RAT; P26772 

Genbank Protein ID

 X71429; BC058492 

Genbank Nucleotide ID

 CAA50560.1; AAH58492.1 

Protein Name

 10 kDa heat shock protein, mitochondrial 

Protein Synonyms/Alias

 Hsp10; 10 kDa chaperonin; Chaperonin 10; CPN10 

Gene Name

 Hspe1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
36	GGIMLPEKSQGKVLQ	acetylation	[1]
40	LPEKSQGKVLQATVV	acetylation	[1]
56	VGSGGKGKGGEIQPV	acetylation	[1]
66	EIQPVSVKVGDKVLL	acetylation	[1]
86	TKVVLDDKDYFLFRD	acetylation	[1]
99	RDGDILGKYVD****	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine.
 MOD_RES 40 40 N6-malonyllysine (By similarity).
 MOD_RES 54 54 N6-malonyllysine (By similarity).
 MOD_RES 56 56 N6-acetyllysine; alternate (By
 MOD_RES 56 56 N6-malonyllysine; alternate (By
 MOD_RES 79 79 Phosphothreonine (By similarity).
 MOD_RES 86 86 N6-acetyllysine (By similarity).
 MOD_RES 99 99 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Chaperone; Complete proteome; Direct protein sequencing; Mitochondrion; Phosphoprotein; Reference proteome; Stress response. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 102 AA 

Protein Sequence

Gene Ontology

 GO:0005759; C:mitochondrial matrix; IDA:RGD.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0051087; F:chaperone binding; ISS:UniProtKB.
 GO:0006457; P:protein folding; IEA:InterPro.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 

Interpro

 IPR020818; Chaperonin_Cpn10.
 IPR018369; Chaprnonin_Cpn10_CS.
 IPR011032; GroES-like. 

Pfam

 PF00166; Cpn10 

SMART

 SM00883; Cpn10 

PROSITE

 PS00681; CHAPERONINS_CPN10 

PRINTS

 PR00297; CHAPERONIN10.