| Tag | Content |
|---|
| CPLM ID | CPLM-013009 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Lethal(2) giant larvae protein homolog 2 |
Protein Synonyms/Alias | Lethal giant larvae-like protein 2 |
Gene Name | Llgl2 |
Gene Synonyms/Alias | Llglh2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 684 | QAQAVNIKAERTGLQ | ubiquitination | [1] | | 828 | FKVFTLPKVSAKLKL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity (By similarity). |
Sequence Annotation | REPEAT 36 69 WD 1.
REPEAT 76 117 WD 2.
REPEAT 132 169 WD 3.
REPEAT 193 227 WD 4.
REPEAT 233 268 WD 5.
REPEAT 282 324 WD 6.
REPEAT 332 366 WD 7.
REPEAT 388 464 WD 8.
REPEAT 508 583 WD 9.
REPEAT 592 653 WD 10.
REPEAT 715 771 WD 11.
REPEAT 780 832 WD 12.
REPEAT 837 890 WD 13.
REPEAT 904 927 WD 14.
MOD_RES 653 653 Phosphoserine (By similarity).
MOD_RES 1022 1022 Phosphoserine (By similarity). |
Keyword | Cell cycle; Cell division; Complete proteome; Cytoplasm; Exocytosis; Phosphoprotein; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1027 AA |
Protein Sequence | MRRFLRTGHD PARERLKRDL FQFNKTVEHG FPHQPSALGY SPSLRILAIG TRSGAVKLYG 60
APGVEFMGLH KENNAVLQIH FLPGQCQLVT LLDDNSLHLW SLKVKGGVSE LQEEESFTLR 120
GPPGAAPSAT QVTEILPHSS GELLYLGTES GNVFVVQLPG FRTLHDRTIC SDEVLQWLPE 180
EARHRRVFEM VEALQEHPRD PNQILIGYSR GLVVIWDLQG SRALSHFLSS QQLENASWQR 240
DGCLIVTCHS DGSHCQWPVS SDTQNPEPLR SSIPYGPFPC KAITKIFWLT TRQGLPFTIF 300
QGGMPRASYG DRHCISVVHN GQQTAFDFTS RVIDFTVLSE ADPAAAFDDP YALVVLAEEE 360
LVVIDLQTPG WPPVQLPYLA SLHCSAITCS HHVSNIPLKL WERIIAAGSR QNSHFSTMEW 420
PIDGGTSLAP PPPQRDLLLT GHEDGTVRFW DASGVCLRLL YKLSTVRVFL TDTDPSENLI 480
AQGEDEWPPL RKVGSFDPYS DDPRLGIQKI FLCKYSGYLA VAGTAGQVLV LELNDEAAEH 540
AVEQVEADLL QDQEGYRWKG HERLAARPGP VCFEAGFQPF VLVQCQPPAV VTSLALHSEW 600
RLVAFGTSHG FGLFDHQQRR QVFVKCTLHP SDQLALEGPL SRVKSLKKSL RQSFRRMRRS 660
RVSSHKRRPG GPTGEAQAQA VNIKAERTGL QNMELAPVQR KIEARSAEDS FTGFVRTLYF 720
ADTYLRDSSR HCPSLWAGTN GGTVYAFSLR VPPAERRTDE PVRAEQAKEI QLMHRAPVVG 780
ILVLDGHNVP LPEPLEVAHD LSKSPDMQGS HQLLVVSEEQ FKVFTLPKVS AKLKLKLTAL 840
EGSRVRRVGV AHFGSCRAED YGEHHLAVLT NLGDIQVVSM PLLKPQVRYS CIRREDVSGI 900
ASCVFTKYGQ GFYLISPSEF ERFSLSTKWL VEPRCLVDST KAKKHNRPSN GNGTGLKMTS 960
SGHVRNSKSQ SDGDEKKPGP VMEHALLNDA WVLKEIQSTL EGDRRSYGNW HPHRVAVGCR 1020
LSNGEAE 1027 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |