CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015195
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Thioredoxin domain-containing protein 15 
Protein Synonyms/Alias
  
Gene Name
 Txndc15 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
256ILLFQGAKPMARFNHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 DOMAIN 163 280 Thioredoxin.
 CARBOHYD 171 171 N-linked (GlcNAc...) (Potential).
 CARBOHYD 178 178 N-linked (GlcNAc...) (Potential).
 CARBOHYD 190 190 N-linked (GlcNAc...) (Potential).
 CARBOHYD 277 277 N-linked (GlcNAc...).  
Keyword
 Complete proteome; Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 344 AA 
Protein Sequence
MQLLCWWQVL LWVLGLPAHG LEVAEDSGHP WREERPVPAL QVGAVYLHEE EVAQDHRDQA 60
RAAEPMEASL GPRGDPMVVL SVVPGAAEDQ RSPEAHDGTC SAQGEEDPSC GRENLFGLQG 120
AGGFQDREEE YYAEPGVTEA EPVATEDANS TDSLKSPKVN CEERNVTGLE NFTLKILNMS 180
QDLMDFLNPN GSDCTLVLFY TPWCRFSASL APHFNSLPRA FPTLGFLALD ASQHSSLSTR 240
FGTVAVPNIL LFQGAKPMAR FNHTDRTLET LKIFIFNQTG IEAKKNVVVT QADQMGPLPS 300
TLIKTVDWLL VFSLFFLISF IMYATIRTES IRWLIPGQEQ EHAE 344 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0045454; P:cell redox homeostasis; IEA:InterPro. 
Interpro
 IPR012336; Thioredoxin-like_fold.
 IPR013766; Thioredoxin_domain. 
Pfam
 PF00085; Thioredoxin 
SMART
  
PROSITE
 PS51352; THIOREDOXIN_2 
PRINTS