CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031524
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Apoptosis inhibitor 5 
Protein Synonyms/Alias
 cDNA FLJ51754, highly similar to Apoptosis inhibitor 5 
Gene Name
 API5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
25QVILDGVKGGTKEKRubiquitination[1]
40LAAQFIPKFFKHFPEubiquitination[1]
43QFIPKFFKHFPELADubiquitination[2]
73SIRRQAIKELPQFATubiquitination[1]
142IVRERAIKFLSTKLKubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 513 AA 
Protein Sequence
MKQRWRENGI GKHKDAYQVI LDGVKGGTKE KRLAAQFIPK FFKHFPELAD SAINAQLDLC 60
EDEDVSIRRQ AIKELPQFAT GENLPRVADI LTQLLQTDDS AEFNLVNNAL LSIFKMDAKG 120
TLGGLFSQIL QGEDIVRERA IKFLSTKLKT LPDEVLTKEV EELILTESKK VLEDVTGEEF 180
VLFMKILSGL KSLQTVSGRQ QLVELVAEQA DLEQTFNPSD PDCVDRLLQC TRQAVPLFSK 240
NVHSTRFVTY FCEQVLPNLG TLTTPVEGLD IQLEVLKLLA EMSSFCGDME KLETNLRKLF 300
DKLLEYMPLP PEEAENGENA GNEEPKLQFS YVECLLYSFH QLGRKLPDFL TAKLNAEKLK 360
DFKIRLQYFA RGLQVYIRQL RLALQGKTGE ALKTEENKIK VVALKITNNI NVLIKDLFHI 420
PPSYKSTVTL SWKPVQKVEI GQKRASEDTT SGSPPKKSSA GPKRDARQIY NPPSGKYSSN 480
LGNFNYEQRG AFRGSRGGRG WGTRGNRSRG RLY 513 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR008383; API5.
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold. 
Pfam
 PF05918; API5 
SMART
  
PROSITE
  
PRINTS