| Tag | Content |
|---|
| CPLM ID | CPLM-013624 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Serine/threonine-protein phosphatase 6 regulatory subunit 3 |
Protein Synonyms/Alias | SAPS domain family member 3; Sporulation-induced transcript 4-associated protein SAPL |
Gene Name | PPP6R3 |
Gene Synonyms/Alias | C11orf23; KIAA1558; PP6R3; SAPL; SAPS3 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 190 | LNWLNEEKIIQRLVE | ubiquitination | [1] | | 435 | ALVQQLIKDLPDEVR | ubiquitination | [1] |
|
Reference | [1] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI. J Proteome Res. 2012 Feb 3;11(2):796-807. [ PMID: 22053931] |
Functional Description | Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. May have an important role in maintaining immune self-tolerance. |
Sequence Annotation | MOD_RES 579 579 Phosphoserine.
MOD_RES 617 617 Phosphoserine.
MOD_RES 722 722 Phosphoserine.
MOD_RES 853 853 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 873 AA |
Protein Sequence | MFWKFDLHSS SHIDTLLERE DVTLKELMDE EDVLQECKAQ NRKLIEFLLK AECLEDLVSF 60
IIEEPPQDMD EKIRYKYPNI SCELLTSDVS QMNDRLGEDE SLLMKLYSFL LNDSPLNPLL 120
ASFFSKVLSI LISRKPEQIV DFLKKKHDFV DLIIKHIGTS AIMDLLLRLL TCIEPPQPRQ 180
DVLNWLNEEK IIQRLVEIVH PSQEEDRHSN ASQSLCEIVR LSRDQMLQIQ NSTEPDPLLA 240
TLEKQEIIEQ LLSNIFHKEK NESAIVSAIQ ILLTLLETRR PTFEGHIEIC PPGMSHSACS 300
VNKSVLEAIR GRLGSFHELL LEPPKNMFFK YTWNNFLHTQ VEICIALILA SPFENTENAT 360
ITDQDSTGDN LLLKHLFQKC QLIERILEAW EMNEKKQAEG GRRHGYMGHL TRIANCIVHS 420
TDKGPNSALV QQLIKDLPDE VRERWETFCT SSLGETNKRN TVDLAFSDYQ MQQMTSNFID 480
QFGFNDEKFA DQDDIGNVSF DRVSDINFTL NTNESGNIAL FEACCKERIQ QFDDGGSDEE 540
DIWEEKHIAF TPESQRRSSS GSTDSEESTD SEEEDGAKQD LFEPSSANTE DKMEVDLSEP 600
PNWSANFDVP METTHGAPLD SVGSDVWSTE EPMPTKETGW ASFSEFTSSL STKDSLRSNS 660
PVEMETSTEP MDPLTPSAAA LAVQPEAAGS VAMEASSDGE EDAESTDKVT ETVMNGGMKE 720
TLSLTVDAKT ETAVFKSEEG KLSTSQDAAC KDAEECPETA EAKCAAPRPP SSSPEQRTGQ 780
PSAPGDTSVN GPV 793 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0043666; P:regulation of phosphoprotein phosphatase activity; IDA:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |