| Tag | Content |
|---|
| CPLM ID | CPLM-022326 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Myotubularin-related protein 10 |
Protein Synonyms/Alias | |
Gene Name | MTMR10 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 8 | MFSLKPPKPTFRSYL | ubiquitination | [1] |
|
Reference | [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C. Nat Cell Biol. 2012 Oct;14(10):1089-98. [ PMID: 23000965] |
Functional Description | Probable pseudophosphatase. Contains a Glu residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase (Potential). |
Sequence Annotation | DOMAIN 221 661 Myotubularin phosphatase. |
Keyword | Alternative splicing; Complete proteome; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 777 AA |
Protein Sequence | MFSLKPPKPT FRSYLLPPPQ TDDKINSEPK IKKLEPVLLP GEIVVNEVNF VRKCIATDTS 60
QYDLWGKLIC SNFKISFITD DPMPLQKFHY RNLLLGEHDV PLTCIEQIVT VNDHKRKQKV 120
LGPNQKLKFN PTELIIYCKD FRIVRFRFDE SGPESAKKVC LAIAHYSQPT DLQLLFAFEY 180
VGKKYHNSAN KINGIPSGDG GGGGGGGNGA GGGSSQKTPL FETYSDWDRE IKRTGASGWR 240
VCSINEGYMI STCLPEYIVV PSSLADQDLK IFSHSFVGRR MPLWCWSHSN GSALVRMALI 300
KDVLQQRKID QRICNAITKS HPQRSDVYKS DLDKTLPNIQ EVQAAFVKLK QLCVNEPFEE 360
TEEKWLSSLE NTRWLEYVRA FLKHSAELVY MLESKHLSVV LQEEEGRDLS CCVASLVQVM 420
LDPYFRTITG FQSLIQKEWV MAGYQFLDRC NHLKRSEKES PLFLLFLDAT WQLLEQYPAA 480
FEFSETYLAV LYDSTRISLF GTFLFNSPHQ RVKQSTEFAI SKNIQLGDEK GLKFPSVWDW 540
SLQFTAKDRT LFHNPFYIGK STPCIQNGSV KSFKRTKKSY SSTLRGMPSA LKNGIISDQE 600
LLPRRNSLIL KPKPDPAQQT DSQNSDTEQY FREWFSKPAN LHGVILPRVS GTHIKLWKLC 660
YFRWVPEAQI SLGGSITAFH KLSLLADEVD VLSRMLRQQR SGPLEACYGE LGQSRMYFNA 720
SGPHHTDTSG TPEFLSSSFP FSPVGNLCRR SILGTPLSKF LSGAKIWLST ETLANED 777 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |