| Tag | Content |
|---|
| CPLM ID | CPLM-003612 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | tRNA (guanosine(18)-2'-O)-methyltransferase |
Protein Synonyms/Alias | tRNA [Gm18] methyltransferase |
Gene Name | trmH |
Gene Synonyms/Alias | spoU; b3651; JW3626 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 29 | VCMEQVHKPHNVSAI | acetylation | [1] | | 74 | SNSWVQVKTHRTIGD | acetylation | [1] | | 197 | GGYPVLAKVAKRKGL | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Specifically methylates guanosine-18 in various tRNAs. |
Sequence Annotation | BINDING 119 119 S-adenosyl-L-methionine; via carbonyl
BINDING 139 139 S-adenosyl-L-methionine; via amide
BINDING 148 148 S-adenosyl-L-methionine; via amide |
Keyword | Complete proteome; Cytoplasm; Methyltransferase; Reference proteome; S-adenosyl-L-methionine; Transferase; tRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 229 AA |
Protein Sequence | MNPTRYARIC EMLARRQPDL TVCMEQVHKP HNVSAIIRTA DAVGVHEVHA VWPGSRMRTM 60
ASAAAGSNSW VQVKTHRTIG DAVAHLKGQG MQILATHLSD NAVDFREIDY TRPTCILMGQ 120
EKTGITQEAL ALADQDIIIP MIGMVQSLNV SVASALILYE AQRQRQNAGM YLRENSMLPE 180
AEQQRLLFEG GYPVLAKVAK RKGLPYPHVN QQGEIEADAD WWATMQAAG 229 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0003723; F:RNA binding; IEA:InterPro. GO:0009020; F:tRNA (guanosine-2'-O-)-methyltransferase activity; IMP:EcoliWiki. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |