CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032685
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ubiquitin carboxyl-terminal hydrolase 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_083190 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
1980SGEHAAEKTASADGAacetylation[1]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2124 AA 
Protein Sequence
MSRRERKGAN ELNKSDPNCV PPSLLDSQLA LLAANSFDVP LTLKKSTASL SASRSSSPRS 60
VVSANCSSPR TSDFPDRDPL ASSVDLPRAS PASPASPASV SPRSLGSRSP VSSSFAGNLR 120
EREGVCLRGA LHLSPSCGAA LGSLSPPPLL RTSRSACLSP SVSTYPPRAS PLGVSFLSST 180
MEEDDAALFK VEKGSSRLAA KAPEAGATAG ELGVCTPVPG VTPEPSGGVS PPAPKAFGLA 240
SSTPRRLNDG SLLEAPLSNE LEMVIPRFRA RFLEGLEEGD APVDSLTLYS DWKELPALRF 300
RLMVHPLTRS HSRLAQLSPP SPLLPEARAL SPQQQEFLQS RTAAAFVEIG PKPDWPADWS 360
FQAGVRFHIY VVNLSEPERS IWKEETFQFS CEEVDRGWHS IVSYWTLYEE RFFASQSGDL 420
VLRAAVFPAG TAVMSRGLRT PCPPSPPCVR GAATTPAPEA AEAARATEAE MRDKSDREKD 480
DELGPVIAGP PAGASSPLAS LLASLPASAS LGRAGKGYVG LRNHGATCYM NALLQSLYYI 540
GKFRQAVYAL TFDTKAISGP RSVQVLESSR FKSGGSGRDS DNASAYCSPA PHPLAALLVN 600
SDDEEEDFSD WNEQDMRDLL LEEEQEQRRP PSISLALQNL FFRLYTSEEP VACRDLIRSF 660
GWDAADAFTQ QDTHELLKLL LDKVEEQMQG TPAEGSVKKM FEGEMETYIE CIEVDYKSVR 720
KETYEDLNLD VKGCSTIQES LRRLVQPEIL EGENSYDAEA FGKQRARKGV RFLRFPPVCI 780
FLLKRFDFDY EKMDTVKVFS SFEFQSELDL NEFCPGAGVY ELHAVSVHQG DVNSGHYYCF 840
LRPPPRTQWV RFDDDKVYPV SEYAAIGDNF GGDEEDPCNY LAGEFRFFRL QSSRAPRSRQ 900
KVYNAYILVY VKKRLANQLL ADCNPMKVNP QVVIRCRTEE LLMKLRNRIR RVLEQRIKVK 960
VYHPLQFVNR RFLDLPLATM RPLLELKSSR SVGILPIHEQ ITARLFSKLY GEEGTGGEGG 1020
ACSQRAGKAS PPIAFLLYAM DFLADDARFS PLSLADNPCL GEIFRAKMVG NSGRAGGVLG 1080
ARVYPGGASD LNYPYNRFDA CLYFLAVPET NAVIREAVDH DEFCRRHQLL FLKYFDVFSA 1140
NTVLVEASEP VAPQDPKGQR NRQEDDAPVC AALAKKVGED PSDVPEALRD NNIICLDVVL 1200
VPNGWKLVCL QPHLYRLLLR CMEDGLTRPF ALESLRRYVS SLGSLPPLFA ASSSGGSRLF 1260
FPGAGEKRPL VDVATSQSCS LAACAAAYGA GLSATLCGPV FLSTQGNFPA LSSSREQTPE 1320
LPREPALVLA LEIEFQDLKN PTSLTLSSKK TFSQEKATAV VDEKSRASVS PEEGTGVALW 1380
PSSSSPASSS PPSATGAAAQ ALSTAARAAL GDADPLGEKA EEKETLAAKA DETASCSTAD 1440
VSTTVASPMN SGALPPSRAA GLKPDAEAKA GDSLSGQARG SPDGENSKES SPVSLDLPSH 1500
APGGSDGALL PYLSAARGGR IPSDPPEMPV LPSPDFHHYS LNKANRFVFQ FRLYDPLELL 1560
NRPMNCCGML LEDYPRPSVG PSGSSACLAS RDLSLSHCSS NETLSSFTLS STWSATSALT 1620
SDPCLPVSAT KGGNAPSVSA SLVLPTASPS PVTPLAAAGP FGAPAGAATA VGSSGLQRAV 1680
SGAGADLECA DGDATADSEE DEDPWIHVPK GQPVVAKMLE VDVRVACNQV LRYVSWYMGV 1740
DPSRLLLFPE PPLLSDASFA PVTIDSLVCA VSEGGVSRRD GSGGSSPQAS LRRLSVNEVF 1800
SRLEKKALLG AGSRLGRRRP RPAGSFAFAG PAGSRHRIFH LAVLPRHYSL CSRVVDPATL 1860
TPVQLERAKE LVFPVSLGTA AGGASAAALP PEAPLQDPLL HFVVLVFSRR VESLGCVEGL 1920
IPARCPFSSR PLTVKDLIHE ILARMSPALR AQLVDERRRS ASQEGRSISA ETSGEHAAEK 1980
TASADGARVS DAALAGSLRL LESSVASLHD LEKTQQIQSL ALYAGQSGRR LDGPSTQNLF 2040
AVPLRLELDW TPEEKESIEN GELKVLQVVH QTPADREYFG YPFEILVRPS DTLNEIKHKV 2100
KEKLLLPKPL WSNWTFFQYA DCNR 2124 
Gene Ontology
 GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
 GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR018200; Pept_C19ubi-hydrolase_C_CS.
 IPR001394; Peptidase_C19. 
Pfam
 PF00443; UCH 
SMART
  
PROSITE
 PS00972; UCH_2_1
 PS00973; UCH_2_2
 PS50235; UCH_2_3 
PRINTS