CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032859
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Hexokinase 
Protein Synonyms/Alias
  
Gene Name
 PFF1155w 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
35ELSWRINKFVNQLRIacetylation[1]
145HEKGLLDKHATASQLacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Glycolysis; Kinase; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 493 AA 
Protein Sequence
MSEYDIAKND VTYTKLDTIE CDIPINEELS WRINKFVNQL RISYSTLEEF VDNFVYELKK 60
GLEAHRKHPN LWIPHECSFK MLDSCIANIP TGQEKGTYYA IDFGGTNFRA VRASLDGKGK 120
IKRDQETYSL KFTGSYSHEK GLLDKHATAS QLFDHFAERI KYIMGEFNDL DNKEVKSVGF 180
TFSFPCTSPS INCSILIDWT KGFETGRATN DPVEGRDVCK LMNDAFVRAA IPAKVCCVLN 240
DAVGTLMSCA YQKGRGTPPC YIGIILGTGS NGCYYEPEWK KYKYAGKIIN IEFGNFDKDL 300
PTSPIDLVMD WYSANRSRQL FEKMISGAYL GEIVRRFMVN VLQSACSKKM WISDSFNSES 360
GSVVLNDTSK NFEDSRKVAK AAWDMDFTDE QIYVLRKICE AVYNRSAALA AGTIAAIAKR 420
IKIIEHSKFT CGVDGSLFVK NAWYCKRLQE HLKVILADKA ENLIIIPADD GSGKGAAITA 480
AVIALNADIP QLP 493 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004396; F:hexokinase activity; IEA:EC.
 GO:0006096; P:glycolysis; IEA:UniProtKB-KW. 
Interpro
 IPR001312; Hexokinase.
 IPR022673; Hexokinase_C.
 IPR019807; Hexokinase_CS.
 IPR022672; Hexokinase_N. 
Pfam
 PF00349; Hexokinase_1
 PF03727; Hexokinase_2 
SMART
  
PROSITE
 PS00378; HEXOKINASES 
PRINTS
 PR00475; HEXOKINASE.