CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030110
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Inositol 1,4,5-trisphosphate receptor type 2 
Protein Synonyms/Alias
  
Gene Name
 Itpr2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
551SYFERLSKFQDGSNNubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 633 AA 
Protein Sequence
HGNDIASLFE LDATTLQRAD CLVPRNSYVR LRHLCTNTWV TSTTIPIDTE EERPVMLKIG 60
TCQTKEDKEA FAIVCVPLSE VRDLDFANDA NKVLATTVKK LENGSITQNE RRFVTKLLED 120
LIFFVADVTN NGQDVLDVVI TKPNRERQKL MREQNILAQV FGILKAPFKE KAGEGSMLRL 180
EDLGDQRYAP YKYVLRLCYR VLRHSQQDYR KNQEYIAKNF CVMQSQIGYD ILAEDTITAL 240
LHNNRKLLEK HITAKEIETF VSLLRRNREP RFLDYLSDLC VSNSTAIPVT QELICKFMLS 300
PGNADILIQT KLVSMQVENP MESSILPDDI DDEEVWLYWI DSNKEPHGKA IRHLAQEARE 360
GTKADLEVLT YYRYQLNLFA RMCLDRQYLA INQISTQLSV DLILRCVSDE SLPFDLRASF 420
CRLMLHMHVD RDPQESVVPV RYARLWTEIP TKITIHEYDS ITDSSRNDMK RKFALTMEFV 480
EEYLKEVVNQ PFPFGDKEKN KLTFEVVHLA RNLIYFGFYS FSELLRLTRT LLAILDIVQA 540
PMSSYFERLS KFQDGSNNVM RTIHGVGEMM TQMVLSRGSI FPVSVPDAQP IVHPSKQASP 600
GEQEDVTVMD TKLKVIEILQ TLRATLQQPL ELH 633 
Gene Ontology
 GO:0005938; C:cell cortex; IDA:MGI.
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0016529; C:sarcoplasmic reticulum; IDA:MGI.
 GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IDA:MGI.
 GO:0035091; F:phosphatidylinositol binding; IDA:MGI.
 GO:0071361; P:cellular response to ethanol; IMP:MGI. 
Interpro
 IPR000699; Ca-rel_channel.
 IPR016093; MIR_motif.
 IPR015925; Ryanodine_recept-rel. 
Pfam
 PF02815; MIR
 PF01365; RYDR_ITPR 
SMART
  
PROSITE
  
PRINTS