UniProt Accession

 RPF1_YEAST; P38805; D3DL40 

Genbank Protein ID

 U00060; BK006934 

Genbank Nucleotide ID

 AAB68926.1; DAA06784.1 

Protein Name

 Ribosome production factor 1 

Protein Synonyms/Alias

 Ribosome biogenesis protein RPF1 

Gene Name

 RPF1 

Gene Synonyms/Alias

 YHR088W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
53	ELREQRLKENVTQTI	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Essential protein. Required for biogenesis of the 60S ribosomal subunit. 

Sequence Annotation

 DOMAIN 93 276 Brix.
 REGION 254 271 RNA-binding.  

Keyword

 Complete proteome; Nucleus; Reference proteome; Ribosome biogenesis; RNA-binding; rRNA processing; rRNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 295 AA 

Protein Sequence

Gene Ontology

 GO:0005730; C:nucleolus; IDA:SGD.
 GO:0030687; C:preribosome, large subunit precursor; IDA:SGD.
 GO:0042134; F:rRNA primary transcript binding; IPI:SGD.
 GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0000027; P:ribosomal large subunit assembly; IPI:SGD.
 GO:0000055; P:ribosomal large subunit export from nucleus; IMP:SGD. 

Interpro

 IPR004154; Anticodon-bd.
 IPR007109; Brix. 

Pfam

 PF04427; Brix 

SMART

 SM00879; Brix 

PROSITE

 PS50833; BRIX 

PRINTS