UniProt Accession

 GORS2_HUMAN; Q9H8Y8; Q53TE3; Q96I74; Q96K84; Q9H946; Q9UFW4 

Genbank Protein ID

 AK027349; AK023082; AK023201; AL117430; AC010092; CH471058; BC007770 

Genbank Nucleotide ID

 BAB55054.1; BAB14395.1; BAB14459.1; CAB55919.1; AAY15076.1; EAX11227.1; AAH07770.1 

Protein Name

 Golgi reassembly-stacking protein 2 

Protein Synonyms/Alias

 GRS2; Golgi phosphoprotein 6; GOLPH6; Golgi reassembly-stacking protein of 55 kDa; GRASP55; p59 

Gene Name

 GORASP2 

Gene Synonyms/Alias

 GOLPH6 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
143	TRPFEEGKKISLPGQ	ubiquitination	[1]
144	RPFEEGKKISLPGQM	ubiquitination	[1]
352	DVTPPTAKAPTTVED	ubiquitination	[1]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA. 

Sequence Annotation

 DOMAIN 5 75 PDZ.
 REGION 194 199 Important for membrane binding.
 MOD_RES 30 30 Omega-N-methylated arginine (By
 MOD_RES 47 47 Omega-N-methylated arginine (By
 MOD_RES 214 214 Phosphoserine.
 MOD_RES 222 222 Phosphothreonine.
 MOD_RES 225 225 Phosphothreonine.
 MOD_RES 409 409 Phosphoserine (By similarity).
 MOD_RES 415 415 Phosphothreonine.
 MOD_RES 433 433 Phosphothreonine.
 MOD_RES 436 436 Phosphoserine.
 MOD_RES 449 449 Phosphoserine.
 MOD_RES 451 451 Phosphoserine.
 LIPID 2 2 N-myristoyl glycine (Probable).  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Direct protein sequencing; Golgi apparatus; Lipoprotein; Membrane; Methylation; Myristate; Palmitate; Phosphoprotein; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 452 AA 

Protein Sequence

Gene Ontology

 GO:0000139; C:Golgi membrane; TAS:Reactome.
 GO:0000278; P:mitotic cell cycle; TAS:Reactome.
 GO:0006996; P:organelle organization; IMP:UniProtKB. 

Interpro

 IPR024958; GRASP55/65_PDZ.
 IPR007583; GRASP55_65.
 IPR001478; PDZ. 

Pfam

 PF04495; GRASP55_65 

SMART

 SM00228; PDZ 

PROSITE

 PS50106; PDZ 

PRINTS