CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029669
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Copine-1 
Protein Synonyms/Alias
 HCG38213, isoform CRA_b 
Gene Name
 CPNE1 
Gene Synonyms/Alias
 hCG_38213 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
65CSSPEFSKTLQLEYRubiquitination[1]
78YRFETVQKLRFGIYDubiquitination[1]
140TVSAQELKDNRVVTMubiquitination[1]
162DKKDFLGKSDPFLEFubiquitination[1]
195NNLNPTWKRFSVPVQubiquitination[1]
527AQGWAPLKPLPPSAKubiquitination[1]
534KPLPPSAKDPAQAPQubiquitination[1]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 542 AA 
Protein Sequence
MKMMHMAHCV TLVQLSISCD HLIDKDIGSK SDPLCVLLQD VGGGSWAELG RTERVRNCSS 60
PEFSKTLQLE YRFETVQKLR FGIYDIDNKT PELRDDDFLG GAECSLGQIV SSQVLTLPLM 120
LKPGKPAGRG TITVSAQELK DNRVVTMEVE ARNLDKKDFL GKSDPFLEFF RQGDGKWHLV 180
YRSEVIKNNL NPTWKRFSVP VQHFCGGNPS TPIQVQCSDY DSDGSHDLIG TFHTSLAQLQ 240
AVPAEFECIH PEKQQKKKSY KNSGTIRVKI CRVETEYSFL DYVMGGCQIN FTVGVDFTGS 300
NGDPSSPDSL HYLSPTGVNE YLMALWSVGS VVQDYDSDKL FPAFGFGAQV PPDWQVSHEF 360
ALNFNPSNPY CAGIQGIVDA YRQALPQVRL YGPTNFAPII NHVARFAAQA AHQGTASQYF 420
MLLLLTDGAV TDVEATREAV VRASNLPMSV IIVGVGGADF EAMEQLDADG GPLHTRSGQA 480
AARDIVQFVP YRRFQNAPRE ALAQTVLAEV PTQLVSYFRA QGWAPLKPLP PSAKDPAQAP 540
QA 542 
Gene Ontology
  
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR018029; C2_membr_targeting.
 IPR010734; Copine.
 IPR002035; VWF_A. 
Pfam
 PF00168; C2
 PF07002; Copine 
SMART
 SM00239; C2
 SM00327; VWA 
PROSITE
 PS50004; C2 
PRINTS