CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043200
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 cAMP-dependent protein kinase type II-beta regulatory subunit 
Protein Synonyms/Alias
  
Gene Name
 Prkar2b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
14AMFEKLVKEGEHVIDubiquitination[1]
197ELALVTNKPRAASAHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 256 AA 
Protein Sequence
MSQVLDAMFE KLVKEGEHVI DQGDDGDNFY VIDRGTFDIY VKCDGVGRCV GNYDNRGSFG 60
ELALMYNTPR AATITATSPG ALWGLDRVTF RRIIVKNNAK KRKMYESFIE SLPFLKSLEV 120
SERLKVVDVI GTKVYNDGEQ IIAQGDLADS FFIVESGEVK ITMKRKGKSE VEENGAVEIA 180
RCFRGQYFGE LALVTNKPRA ASAHAIGTVK CLAMDVQAFE RLLGPCMEIM KRNIATYEEQ 240
LVALFGTNMD IVEPTA 256 
Gene Ontology
 GO:0005952; C:cAMP-dependent protein kinase complex; IEA:Compara.
 GO:0005813; C:centrosome; IEA:Compara.
 GO:0045121; C:membrane raft; IEA:Compara.
 GO:0005743; C:mitochondrial inner membrane; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0030552; F:cAMP binding; IEA:Compara.
 GO:0008603; F:cAMP-dependent protein kinase regulator activity; IDA:MGI.
 GO:0008283; P:cell proliferation; TAS:MGI.
 GO:0006631; P:fatty acid metabolic process; IMP:MGI.
 GO:0007612; P:learning; IMP:MGI.
 GO:0009887; P:organ morphogenesis; TAS:MGI.
 GO:0006468; P:protein phosphorylation; TAS:MGI.
 GO:0097332; P:response to antipsychotic drug; IEA:Compara.
 GO:0097338; P:response to clozapine; IEA:Compara. 
Interpro
 IPR002373; cAMP/cGMP_kin.
 IPR018490; cNMP-bd-like.
 IPR018488; cNMP-bd_CS.
 IPR000595; cNMP-bd_dom.
 IPR014710; RmlC-like_jellyroll. 
Pfam
 PF00027; cNMP_binding 
SMART
 SM00100; cNMP 
PROSITE
 PS00888; CNMP_BINDING_1
 PS00889; CNMP_BINDING_2
 PS50042; CNMP_BINDING_3 
PRINTS
 PR00103; CAMPKINASE.