UniProt Accession

 GCSH_RAT; Q5I0P2 

Genbank Protein ID

 BC088114 

Genbank Nucleotide ID

 AAH88114.1 

Protein Name

 Glycine cleavage system H protein, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 Gcsh 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
49	SALLSVRKFTEKHEW	acetylation	[1]
53	SVRKFTEKHEWVTAK	acetylation	[1]
163	MSEEAYEKYVKSIEE	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity). 

Sequence Annotation

 MOD_RES 104 104 N6-lipoyllysine (By similarity).  

Keyword

 Complete proteome; Lipoyl; Mitochondrion; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 170 AA 

Protein Sequence

Gene Ontology

 GO:0005960; C:glycine cleavage complex; IC:RGD.
 GO:0005739; C:mitochondrion; IDA:RGD.
 GO:0004047; F:aminomethyltransferase activity; IMP:RGD.
 GO:0019464; P:glycine decarboxylation via glycine cleavage system; IMP:RGD. 

Interpro

 IPR003016; 2-oxoA_DH_lipoyl-BS.
 IPR002930; GCV_H.
 IPR017453; GCV_H_sub.
 IPR011053; Single_hybrid_motif. 

Pfam

 PF01597; GCV_H 

SMART

  

PROSITE

 PS00189; LIPOYL 

PRINTS