CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042220
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 L-lactate dehydrogenase 
Protein Synonyms/Alias
  
Gene Name
 LOC100713875 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Cavia porcellus (Guinea pig) 
NCBI Taxa ID
 10141 
Lysine Modification
Position
Peptide
Type
References
87TPKIVSGKDYNVTANacetylation[1]
132FIIPNVVKYSPNCKLacetylation[1]
230ELGTDGDKEHWKEVHacetylation[1]
Reference
 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Glycolysis; NAD; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 338 AA 
Protein Sequence
FGSKSKMASL KDQLIVNLLK EEQVPQNKIT VVGVGAVGMA CAISILMKDL ADELALVDVM 60
EDKLKGEMMD LQHGSLFLRT PKIVSGKDYN VTANSKLVII TAGARQQEGE SRLNLVQRNV 120
NIFKFIIPNV VKYSPNCKLL VVSNPVDILT YVAWKISGFP KNRVIGSGCN LDSARFRYLM 180
GERLGVHPLS CHGWILGEHG DSSVPVWSGV NVAGVALKNL HPELGTDGDK EHWKEVHKQV 240
VDSAYEVIKL KGYTSWAIGL SVADLAESIM KNLRRVHPIS TMIKGLYGIK DDVFLSVPCV 300
LGQNGISDVV KVTLTPDEEA RLKKSADTLW GIQKELQF 338 
Gene Ontology
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0004459; F:L-lactate dehydrogenase activity; IEA:EC.
 GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
 GO:0031668; P:cellular response to extracellular stimulus; IEA:Compara.
 GO:0006096; P:glycolysis; IEA:UniProtKB-KW. 
Interpro
 IPR001557; L-lactate/malate_DH.
 IPR011304; L-lactate_DH.
 IPR018177; L-lactate_DH_AS.
 IPR022383; Lactate/malate_DH_C.
 IPR001236; Lactate/malate_DH_N.
 IPR015955; Lactate_DH/Glyco_Ohase_4_C.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF02866; Ldh_1_C
 PF00056; Ldh_1_N 
SMART
  
PROSITE
 PS00064; L_LDH 
PRINTS
 PR00086; LLDHDRGNASE.