CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010247
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcriptional regulator KdgR 
Protein Synonyms/Alias
  
Gene Name
 kdgR 
Gene Synonyms/Alias
 yebP; b1827; JW1816 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
45SQRVMMSKSTVYRFLacetylation[1]
69AQEGESEKYSLTLKLacetylation[1]
75EKYSLTLKLFELGARacetylation[1]
105RELSRLTKETIHLGAacetylation[1]
123DSIVYIHKIDSMYNLacetylation[1]
161WRDRDEVKQILEGVEacetylation[1]
170ILEGVEYKRSTERTIacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Transcriptional regulator of the kdgK gene for the kdg kinase and the kdgT gene for the kdg permease. 
Sequence Annotation
 DOMAIN 13 74 HTH iclR-type.
 DOMAIN 89 258 IclR-ED.
 DNA_BIND 34 53 H-T-H motif (Potential).  
Keyword
 3D-structure; Complete proteome; DNA-binding; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 263 AA 
Protein Sequence
MANADLDKQP DSVSSVLKVF GILQALGEER EIGITELSQR VMMSKSTVYR FLQTMKTLGY 60
VAQEGESEKY SLTLKLFELG ARALQNVDLI RSADIQMREL SRLTKETIHL GALDEDSIVY 120
IHKIDSMYNL RMYSRIGRRN PLYSTAIGKV LLAWRDRDEV KQILEGVEYK RSTERTITST 180
EALLPVLDQV REQGYGEDNE EQEEGLRCIA VPVFDRFGVV IAGLSISFPT LRFSEERLQE 240
YVAMLHTAAR KISAQMGYHD YPF 263 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:EcoCyc.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:EcoCyc.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR014757; Tscrpt_reg_IclR_C.
 IPR005471; Tscrpt_reg_IclR_N.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF09339; HTH_IclR
 PF01614; IclR 
SMART
 SM00346; HTH_ICLR 
PROSITE
 PS51077; HTH_ICLR
 PS51078; ICLR_ED 
PRINTS