| Tag | Content |
|---|
| CPLM ID | CPLM-010251 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | tRNA (mo5U34)-methyltransferase |
Protein Synonyms/Alias | |
Gene Name | cmoB |
Gene Synonyms/Alias | yecP; b1871; JW1860 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 40 | EQQHGLFKQWSNAVE | acetylation | [1] | | 53 | VEFLPEIKPYRLDLL | acetylation | [1] | | 77 | PLSAGQIKRIETLMR | acetylation | [1] | | 110 | TEWRSDWKWDRVLPH | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity). |
Sequence Annotation | |
Keyword | Complete proteome; Methyltransferase; Reference proteome; S-adenosyl-L-methionine; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 323 AA |
Protein Sequence | MIDFGNFYSL IAKNHLSHWL ETLPAQIANW QREQQHGLFK QWSNAVEFLP EIKPYRLDLL 60
HSVTAESEEP LSAGQIKRIE TLMRNLMPWR KGPFSLYGVN IDTEWRSDWK WDRVLPHLSD 120
LTGRTILDVG CGSGYHMWRM IGAGAHLAVG IDPTQLFLCQ FEAVRKLLGN DQRAHLLPLG 180
IEQLPALKAF DTVFSMGVLY HRRSPLEHLW QLKDQLVNEG ELVLETLVID GDENTVLVPG 240
DRYAQMRNVY FIPSALALKN WLKKCGFVDI RIADVSVTTT EEQRRTEWMV TESLADFLDP 300
HDPGKTVEGY PAPKRAVLIA RKP 323 |
Gene Ontology | GO:0016300; F:tRNA (uracil) methyltransferase activity; IEA:InterPro. GO:0002098; P:tRNA wobble uridine modification; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |