CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027618
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 EH domain containing protein 
Protein Synonyms/Alias
 Putative achaete scute target 1, isoform B 
Gene Name
 Past1 
Gene Synonyms/Alias
 EHD; CG6148; Dmel_CG6148 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
124KQFRPLSKYGNAFLNacetylation[1]
321DMPSVFGKDSKKKDLacetylation[1]
330SKKKDLIKNLGQVYDacetylation[1]
469KISGATAKQELIKSKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 534 AA 
Protein Sequence
MFSFLKREKN TQEVVENVIG ELKKIYRSKL LPLEEHYQFH DFHSPKLEDP DFDAKPMILL 60
VGQYSTGKTT FIRYLLERDF PGIRIGPEPT TDRFIAVMYD DKEGVIPGNA LVVDPKKQFR 120
PLSKYGNAFL NRFQCSSVAS PVLNAISIVD TPGILSGEKQ RIDRGYDFTG VLEWFAERVD 180
RIILLFDAHK LDISDEFRRS IEALKGHDDK IRIILNKADM IDHQQLMRVY GALMWSLGKV 240
LQTPEVARVY IGSFWDQPLR FDANRRLFED EEQDLFRDLQ SLPRNAALRK LNDLIKRARL 300
AKVHAFIIAE LRKDMPSVFG KDSKKKDLIK NLGQVYDRIQ REHSISPGDF PDIKKMQEVL 360
QHQDFTKFHS LKPHLLDIVD NMLAKDIARL MEMIPQEEMT MVADPIVKGG AFEGVIDDHV 420
SPFGYMKGEG IDAGYGEHEW ICNKDKPRTD GIFNGLGPVD GKISGATAKQ ELIKSKLPNS 480
VLSKIWKLSD VDGDGFLDSD EFALALHLIN VKLEGCELPT VLPEHLVPPS KRYD 534 
Gene Ontology
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0006897; P:endocytosis; IMP:FlyBase.
 GO:0006184; P:GTP catabolic process; IEA:GOC.
 GO:0008587; P:imaginal disc-derived wing margin morphogenesis; IGI:FlyBase.
 GO:0007474; P:imaginal disc-derived wing vein specification; IGI:FlyBase.
 GO:0048477; P:oogenesis; IMP:FlyBase.
 GO:0007291; P:sperm individualization; IMP:FlyBase. 
Interpro
 IPR001401; Dynamin_GTPase.
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR000261; EPS15_homology.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00350; Dynamin_N 
SMART
 SM00027; EH 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS50031; EH 
PRINTS