CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034338
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Dgki 
Protein Synonyms/Alias
  
Gene Name
 Dgki 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
379LLVFVNPKSGGNQGTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1050 AA 
Protein Sequence
MDAAGRGCHL LPLPAARGPA RAPAASSALS PTGLCSGTTS ASFAAAGAVA MNPSSSAGEE 60
RGATGGSSSS GSGAGSCCLG AEGGADPRGA GAAAAAALEE PAAAGQKEKE EALEEKLRDL 120
TFRKQVSYRK AISRTGLQHL APAHPLGLPV ANGPAKEPRA TLDWSENAVN GEHLWLETNV 180
SGDLCYLGEE NCQVRFAKSA LRRKCAVCKI VVHTACIEQL EKINFRCKPT FREGGSRSPR 240
ENFVRHHWVH RRRQEGKCKQ CGKGFQQKFS FHSKEIVAIS CSWCKQAFHN KVTCFMLHHI 300
EEPCSLGAHA AVIVPPTWII KVKKPQNSLK ASNRKKKRTS FKRKASKRGT EQETKGRPFV 360
IKPISSPLMK PLLVFVNPKS GGNQGTKVLQ MFMWYLNPRQ VFDLSQEGPK DALEMYRKVP 420
NLRILACGGD GTVGWILSIL DELQLSPQPP VGVLPLGTGN DLARTLNWGG GYTDEPVSKI 480
LCQVEDGTIV QLDRWNLHVE RNPDLPPEEL EDGVCKLPLN VFNNYFSLGF DAHVTLEFHE 540
SREANPEKFN SRFRNKMFYA GAAFSDFLQR SSRDLSKHVK VVCDGTDLTP KIQDLKFQCI 600
VFLNIPRYCA GTMPWGNPGD HHDFEPQRHD DGYIEVIGFT MASLAALQVG GHGERLHQCR 660
EVMLLTYKSI PMQVDGEPCR LAPAMIRISL RNQANMVQKS KRRTSMPLLN DPQSVPDRLR 720
IRVNKISLQD YEGLHYDKDK LREASIPLGI LVVRGDCDLE TCRMYIDRLQ EDLQSVSSGS 780
QRVHYQDQET SFPRALSAQR LSPRWCFLDA TSADRFYRID RSQEHLHFVM EISHDEIFIL 840
DPDMVVSQQA GTPPGMPDLV VEQASGLSDW WNPALRKRML SDSGMITPHY EDSDLKDFSH 900
SRVLQSPVSS EDHAILQAVL TGDLMKLMES YKNGGSLLIQ GPGHCSLLHY AAKTGNGDIV 960
KYILDHGPAE LLDMADSETG ETALHKAACQ RNRAVCQLLV DAGASLRQTD SKGKTPQERA 1020
QQAGDPDLAA YLESRQNYKI IGHEDLETAV 1050 
Gene Ontology
 GO:0032045; C:guanyl-nucleotide exchange factor complex; IDA:MGI.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
 GO:0004143; F:diacylglycerol kinase activity; IDA:MGI.
 GO:0005095; F:GTPase inhibitor activity; IDA:MGI.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro.
 GO:0046579; P:positive regulation of Ras protein signal transduction; IMP:MGI.
 GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
 GO:0032317; P:regulation of Rap GTPase activity; IMP:MGI. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR000756; Diacylglycerol_kin_accessory.
 IPR001206; Diacylglycerol_kinase_cat_dom.
 IPR002219; Prot_Kinase_C-like_PE/DAG-bd. 
Pfam
 PF12796; Ank_2
 PF00130; C1_1
 PF00609; DAGK_acc
 PF00781; DAGK_cat 
SMART
 SM00248; ANK
 SM00109; C1
 SM00045; DAGKa
 SM00046; DAGKc 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS50146; DAGK 
PRINTS