UniProt Accession

 UTER_RAT; P17559 

Genbank Protein ID

 J05536; BC069174; X51318 

Genbank Nucleotide ID

 AAA41817.1; AAH69174.1; CAA35701.1 

Protein Name

 Uteroglobin 

Protein Synonyms/Alias

 Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; PCB-binding protein; Secretoglobin family 1A member 1 

Gene Name

 Scgb1a1 

Gene Synonyms/Alias

 Cc10; Ugb; Utg 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
79	ETRINIVKLTEKILT	acetylation	[1]
83	NIVKLTEKILTSPLC	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. 

Sequence Annotation

 DISULFID 24 24 Interchain (with C-90).
 DISULFID 90 90 Interchain (with C-24).  

Keyword

 3D-structure; Complete proteome; Disulfide bond; Phospholipase A2 inhibitor; Reference proteome; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 96 AA 

Protein Sequence

Gene Ontology

 GO:0005615; C:extracellular space; IDA:RGD.
 GO:0005635; C:nuclear envelope; IDA:RGD.
 GO:0005791; C:rough endoplasmic reticulum; IDA:RGD.
 GO:0030141; C:secretory granule; IDA:RGD.
 GO:0005488; F:binding; IPI:RGD.
 GO:0019834; F:phospholipase A2 inhibitor activity; IEA:UniProtKB-KW.
 GO:0032689; P:negative regulation of interferon-gamma production; IEA:Compara.
 GO:0032696; P:negative regulation of interleukin-13 production; IEA:Compara.
 GO:0032713; P:negative regulation of interleukin-4 production; IEA:Compara.
 GO:0032714; P:negative regulation of interleukin-5 production; IEA:Compara.
 GO:0042130; P:negative regulation of T cell proliferation; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0050727; P:regulation of inflammatory response; IEA:Compara.
 GO:0043488; P:regulation of mRNA stability; IEA:Compara.
 GO:0034097; P:response to cytokine stimulus; IMP:RGD.
 GO:0042493; P:response to drug; IEP:RGD.
 GO:0071774; P:response to fibroblast growth factor stimulus; IEP:RGD.
 GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.
 GO:0032496; P:response to lipopolysaccharide; IEP:RGD.
 GO:0010193; P:response to ozone; IEP:RGD.
 GO:0034021; P:response to silicon dioxide; IEP:RGD.
 GO:0009410; P:response to xenobiotic stimulus; IEP:RGD. 

Interpro

 IPR016126; Secretoglobin.
 IPR000329; Uteroglobin-like.
 IPR006039; Uteroglobin-like_fam.
 IPR006038; Uteroglobin-like_superfam. 

Pfam

 PF01099; Uteroglobin 

SMART

 SM00096; UTG 

PROSITE

 PS51311; SCGB 

PRINTS

 PR00486; UTEROGLOBIN.