CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026405
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Integral membrane protein 2B, isoform CRA_b 
Protein Synonyms/Alias
 Putative transmembrane protein E3-16 
Gene Name
 ITM2B 
Gene Synonyms/Alias
 hCG_30752 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
3*****MVKVTFNSALubiquitination[1]
13FNSALAQKEAKKDEPubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Membrane; Transmembrane. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 266 AA 
Protein Sequence
MVKVTFNSAL AQKEAKKDEP KSGEEALIIP PDAVAVDCKD PDDVVPVGQR RAWCWCMCFG 60
LAFMLAGVIL GGAYLYKYFA LQPDDVYYCG IKYIKDDVIL NEPSADAPAA LYQTIEENIK 120
IFEEEEVEFI SVPVPEFADS DPANIVHDFN KKLTAYLDLN LDKCYVIPLN TSIVMPPRNL 180
LELLINIKAG TYLPQSYLIH EHMVITDRIE NIDHLGFFIY RLCHDKETYK LQRRETIKGI 240
QKREASNCFA IRHFENKFAV ETLICS 266 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IDA:HPA.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0005524; F:ATP binding; IEA:Compara.
 GO:0006915; P:apoptotic process; IEA:Compara.
 GO:0006917; P:induction of apoptosis; IEA:Compara. 
Interpro
 IPR007084; BRICHOS_dom. 
Pfam
 PF04089; BRICHOS 
SMART
 SM01039; BRICHOS 
PROSITE
 PS50869; BRICHOS 
PRINTS