| Tag | Content |
|---|
| CPLM ID | CPLM-016766 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Podocalyxin-like protein 2 |
Protein Synonyms/Alias | Endoglycan |
Gene Name | Podxl2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 532 | QRRMPKLKHVSHGEE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L-selectins (By similarity). |
Sequence Annotation | MOD_RES 93 93 Sulfotyrosine (By similarity).
MOD_RES 113 113 Sulfotyrosine (By similarity).
MOD_RES 569 569 Phosphoserine (By similarity).
MOD_RES 594 594 Phosphoserine.
CARBOHYD 101 101 N-linked (GlcNAc...) (Potential).
CARBOHYD 260 260 N-linked (GlcNAc...) (Potential).
CARBOHYD 394 394 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Cell adhesion; Complete proteome; Disulfide bond; Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Sialic acid; Signal; Sulfation; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 603 AA |
Protein Sequence | MARPLRAARL PPPLLLLLAA GASLGAYAVG VDEPGPEGLT STSLLDLLLP TDFEPLDSEE 60
PSEAMGLDAG LAPGSGFPSE DSEESRLLQP PQYFWEEEEL NGSSLDLGPT ADYVFPDLTE 120
KVASMEDPGQ APDLPNLPSI LPKMDLAEPP WHMPLQEEEE EEEEEEEERE EEEREKEAEE 180
EEEEEELLPV SGSPGATAQA HAPSPSTSSS TSSQSPGATR HRQEDSGDQA TSGMEVESSV 240
KPTLSVPSVT PSTVAPGVQN YSQESGGTEW PTGGLGVQSE VPQGAGEGAT VGAADFDGQQ 300
GALPSSSLPQ TVPPSGTEVP SEGPLYPRIP DSLPPGPQDT ESTPSSATWG QEGLSEQPLE 360
GQAAEAHSLT PWDSTQVICK DWSNLAGKSY IILNMTQNID CEVFRRHRGL RLLALVEEVL 420
PRHRSGHRGD WHISLSKPSE KEQHLLMTLV GEQGVVPTQD VLSMLSGIRR SLEEIGIQNY 480
STTSSCQARA TQVRSDYGTL FVVLVIIGVI CFIIIVLGLL YNCWQRRMPK LKHVSHGEEL 540
RFVENGCHDN PTLDVASDSQ SEMQEKQPSL NGGAINGPSS WSALMGSKRD PEDSDVFEED 600
THL 603 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0050901; P:leukocyte tethering or rolling; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |