CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025811
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 WD repeat-containing protein 1 isoform 1 variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
46KIIGGDPKGNNFLYTubiquitination[1]
56NFLYTNGKCVILRNIubiquitination[1]
113TQKEHLLKYEYQPFAubiquitination[1]
329LDRNNPSKPLHVIKGubiquitination[1]
423YSGQGVVKLDVQPKCubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 624 AA 
Protein Sequence
RAGPGGSRRA RRGNKWARMP YEIKKVFASL PQVERGVSKI IGGDPKGNNF LYTNGKCVIL 60
RNIDNPALAD IYTEHAHQVV VAKYAPSGFY IASGDVSGKL RIWDTTQKEH LLKYEYQPFA 120
GKIKDIAWTE DSKRIAVVGE GREKFGAVFL WDSGSSVGEI TGHNKVINSV DIKQSRPYRL 180
ATGSDDNCAA FFEGPPFKFK FTVGDHSRFV NCVRFSPDGN RFATASADGQ IYIYDGKTGE 240
KVCALGGSKA HDGGIYAISW SPDSTHLLSA SGDKTSKIWD VSVNSVVSTF PMGSTVLDQQ 300
LGCLWQKDHL LSVSLSGYIN YLDRNNPSKP LHVIKGHSKS IQCLTVHKNG GKSYIYSGSH 360
DGHINYWDSE TGENDSFAGK GHTNQVSRMT VDESGQLISC SMDDTVRYTS LMLRDYSGQG 420
VVKLDVQPKC VAVGPGGYAV VVCIGQIVLL KDQRKCFSID NPGYEPEVVA VHPGGDTVAI 480
GGVDGNVRLY SILGTTLKDE GKLLEAKGPV TDVAYSHDGA FLAVCDASKV VTVFSVADGY 540
SENNVFYGHH AKIVCLAWSP DNEHFASGGM DMMVYVWTLS DPETRVKIQD AHRLHHVSSL 600
AWLDEHTLVT TSHDASVKEW TITY 624 
Gene Ontology
  
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR011045; N2O_reductase_N.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.