CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030360
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transporter 
Protein Synonyms/Alias
  
Gene Name
 Slc6a5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
751GRFIERLKLVCSPQPubiquitination[1]
787GTSSLGLKLPVKDLEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Membrane; Symport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 799 AA 
Protein Sequence
MDCSAPKEMN KQPANILEAA VPGHRDSPRA PRTSPEQDLP AEAPTATVQP PRVPRSASTG 60
AQTFQSADAR ACEAQQSGVG FCNLSSPRAQ ATSAALRDLS EGHSAQANPP SGPAGAGNAL 120
HCKIPALRGP EEDANVSVGK GTLEHNNTPA VGWVNMSQST VVLGTDGIAS VLPGSVATTT 180
IPEYEQGDEN KARGNWSSKL DFILSMVGYA VGLGNVWRFP YLAFQNGGGA FLIPYLMMLA 240
LAGLPIFFLE VSLGQFASQG PVSVWKAIPA LQGCGIAMLI ISVLIAIYYN VIICYTLFYL 300
FASFVSVLPW GSCNNPWNTP ECKDKTKLLL DSCVIGDHPK IQIKNSTFCM TAYPNLTMVN 360
FTSQTNKTFV SGSEEYFKYF VLKISAGIEY PGEIRWPLAF CLFLAWVIVY ASLAKGIKSS 420
GKVVYFTATF PYVVLVILLI RGVTLPGAGA GIWYFITPKW EKLTDATVWK DAATQIFFSL 480
SAAWGGLITL SSYNKFHNNC YRDTLIVTCT NSATSIFAGF VIFSVIGFMA NERKVNIENV 540
ADQGPGIAFV VYPEALTRLP LSPFWAIIFF LMLLTLGLDT MFATIETIVT SISDEFPKYL 600
RTHKPVFTLG CCICFFIMGF PMITQGGIYM FQLVDTYAAS YALVIIAIFE LVGISYVYGL 660
QRFCEDIEMM IGFKPNIFWK VCWAFVTPTI LTFILCFSFY QWEPMTYGSY RYPNWSMVLG 720
WLMLACSVIW IPIMFVIKIY LAPGRFIERL KLVCSPQPDW GPFLAQHRGE RYKNMIDPLG 780
TSSLGLKLPV KDLELGTQC 799 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. 
Interpro
 IPR000175; Na/ntran_symport. 
Pfam
 PF00209; SNF 
SMART
  
PROSITE
 PS00610; NA_NEUROTRAN_SYMP_1
 PS00754; NA_NEUROTRAN_SYMP_2
 PS50267; NA_NEUROTRAN_SYMP_3 
PRINTS
 PR00176; NANEUSMPORT.