UniProt Accession

 ARL1_RAT; P61212; P41276 

Genbank Protein ID

 X76920; U12402; BC061553 

Genbank Nucleotide ID

 CAA54245.1; AAA20668.1; AAH61553.1 

Protein Name

 ADP-ribosylation factor-like protein 1 

Protein Synonyms/Alias

  

Gene Name

 Arl1 

Gene Synonyms/Alias

 Arf7 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
152	LPALKDRKWQIFKTS	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 GTP-binding protein. Can activate phospholipase D with very low efficiency (By similarity). Important for normal function of the Golgi apparatus. 

Sequence Annotation

 NP_BIND 24 31 GTP.
 NP_BIND 45 48 GTP.
 NP_BIND 67 71 GTP (By similarity).
 NP_BIND 126 129 GTP.
 NP_BIND 160 161 GTP.
 METAL 31 31 Magnesium.
 METAL 46 46 Magnesium; via carbonyl oxygen.
 METAL 48 48 Magnesium.
 BINDING 70 70 GTP; via amide nitrogen.
 LIPID 2 2 N-myristoyl glycine (Probable).  

Keyword

 3D-structure; Complete proteome; Golgi apparatus; GTP-binding; Lipoprotein; Magnesium; Membrane; Metal-binding; Myristate; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 181 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0005802; C:trans-Golgi network; IDA:RGD.
 GO:0008047; F:enzyme activator activity; ISS:UniProtKB.
 GO:0005525; F:GTP binding; ISS:UniProtKB.
 GO:0003924; F:GTPase activity; ISS:UniProtKB.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0031584; P:activation of phospholipase D activity; ISS:UniProtKB.
 GO:0007030; P:Golgi organization; IMP:RGD.
 GO:0048193; P:Golgi vesicle transport; IMP:RGD.
 GO:0034067; P:protein localization to Golgi apparatus; ISS:UniProtKB.
 GO:0042147; P:retrograde transport, endosome to Golgi; ISS:UniProtKB.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
 GO:0009404; P:toxin metabolic process; ISS:UniProtKB. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR024156; Small_GTPase_ARF.
 IPR006689; Small_GTPase_ARF/SAR. 

Pfam

 PF00025; Arf 

SMART

 SM00177; ARF 

PROSITE

 PS51417; ARF 

PRINTS

 PR00328; SAR1GTPBP.