CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002278
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosomal protein L6-B 
Protein Synonyms/Alias
 L17; RP18; YL16 
Gene Name
 RPL6B 
Gene Synonyms/Alias
 RPL16B; RPL17B; YL16B; YLR448W; L9324.4 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
8MTAQQAPKWYPSEDVubiquitination[1]
19SEDVAAPKKTRKAVRubiquitination[2]
29RKAVRPQKLRASLVPubiquitination[2]
70LLVTGPFKVNGVPLRacetylation[3]
90YVIATSTKVSVEGVNubiquitination[2]
100VEGVNVEKFNVEYFAubiquitination[2]
108FNVEYFAKEKLTKKEacetylation[3]
108FNVEYFAKEKLTKKEubiquitination[1, 2]
117KLTKKEKKEANLFPEubiquitination[2]
128LFPEQQTKEIKTERVacetylation[3]
128LFPEQQTKEIKTERVubiquitination[1, 2]
139TERVEDQKVVDKALLacetylation[3]
139TERVEDQKVVDKALLubiquitination[2]
143EDQKVVDKALLAEIKacetylation[3]
143EDQKVVDKALLAEIKubiquitination[1, 2]
150KALLAEIKKTPLLKQacetylation[3]
150KALLAEIKKTPLLKQubiquitination[2]
156IKKTPLLKQYLSASFubiquitination[2]
166LSASFSLKNGDKPHLubiquitination[2]
175GDKPHLLKF******acetylation[3]
175GDKPHLLKF******ubiquitination[2]
Reference
 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [3] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
  
Sequence Annotation
 MOD_RES 12 12 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 176 AA 
Protein Sequence
MTAQQAPKWY PSEDVAAPKK TRKAVRPQKL RASLVPGTVL ILLAGRFRGK RVVYLKHLED 60
NTLLVTGPFK VNGVPLRRVN ARYVIATSTK VSVEGVNVEK FNVEYFAKEK LTKKEKKEAN 120
LFPEQQTKEI KTERVEDQKV VDKALLAEIK KTPLLKQYLS ASFSLKNGDK PHLLKF 176 
Gene Ontology
 GO:0022625; C:cytosolic large ribosomal subunit; IDA:SGD.
 GO:0003723; F:RNA binding; IDA:SGD.
 GO:0003735; F:structural constituent of ribosome; IDA:SGD.
 GO:0002181; P:cytoplasmic translation; IDA:SGD.
 GO:0000027; P:ribosomal large subunit assembly; IMP:SGD. 
Interpro
 IPR014722; Rib_L2_dom2.
 IPR000915; Ribosomal_L6E. 
Pfam
 PF01159; Ribosomal_L6e 
SMART
  
PROSITE
 PS01170; RIBOSOMAL_L6E 
PRINTS