CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039449
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Lysine-specific histone demethylase 1B 
Protein Synonyms/Alias
  
Gene Name
 KDM1B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
109SHKDGYDKYTTWKKIubiquitination[1]
155RKWRQLTKEIQLTPQubiquitination[2]
165QLTPQIAKTYRCGMKubiquitination[2]
246ADQYLLPKDYHNKSVubiquitination[1]
282KVTVLEAKDRIGGRVubiquitination[2]
293GGRVWDDKSFKGVTVubiquitination[2]
296VWDDKSFKGVTVGRGubiquitination[2]
418PLSEKKMKAINSLGAubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 591 AA 
Protein Sequence
MATPRGRTKK KASFDHSPDS LPLRSSGRQA KKKATETTDE DEDGGSEKKY RKCEKAGCTA 60
TCPVCFASAS ERCAKNGYTS RWYHLSCGEH FCNECFDHYY RSHKDGYDKY TTWKKIWTSN 120
GKTEPSPKAF MADQQLPYWV QCTKPECRKW RQLTKEIQLT PQIAKTYRCG MKPNTAIKPE 180
TSDHCSLPED LEALTPQKCI PHIIVRGLVR IRCVQEVERI LYFMTRKGLI NTGVLSVGAD 240
QYLLPKDYHN KSVIIIGAGP AGLAAARQLH NFGIKVTVLE AKDRIGGRVW DDKSFKGVTV 300
GRGAQIVNGC INNPVALMCE QVSARSWDHN EFFAQFAGDH TLLTPGYSVI IEKLAEGLDI 360
QLKSPQVQCI DYSGDEVQVT TTDGTGYSAQ KVLVTVPLAL LQKGAIQFNP PLSEKKMKAI 420
NSLGAGIIEK IALQFPYRFW DSKVQGADFF GHVPPSASKR GLFAVFYDMD PQKKHSVLMS 480
VIAGEAVASV RTLDDKQVLQ QCMATLRELF KEQEVPDPTK YFVTRWSTDP WIQMAYSFVK 540
TGGSGEAYDI IAEDIQGTVF FAGEATNRHF PQTVTGAYLS GVREASKIAA F 591 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0016491; F:oxidoreductase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR002937; Amino_oxidase.
 IPR009057; Homeodomain-like.
 IPR016040; NAD(P)-bd_dom.
 IPR003042; Rng_hydrolase-like.
 IPR011124; Znf_CW. 
Pfam
 PF01593; Amino_oxidase
 PF07496; zf-CW 
SMART
  
PROSITE
 PS51050; ZF_CW 
PRINTS
 PR00420; RNGMNOXGNASE.