UniProt Accession

 TSNAX_PONAB; Q5RC21 

Genbank Protein ID

 CR858461 

Genbank Nucleotide ID

 CAH90689.1 

Protein Name

 Translin-associated protein X 

Protein Synonyms/Alias

 Translin-associated factor X 

Gene Name

 TSNAX 

Gene Synonyms/Alias

 TRAX 

Created Date

 July 27, 2013 

Organism

 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) 

NCBI Taxa ID

 9601 

Lysine Modification

Position	Peptide	Type	References
150	ISMDEINKQLIFTTE	ubiquitination	[1]
173	PSSDAQDKQFGTWRL	ubiquitination	[1, 2]
261	ENACYALKVRGSEIP	ubiquitination	[1]
269	VRGSEIPKHMLADVF	ubiquitination	[1]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

 Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis (By similarity). 

Sequence Annotation

 REGION 73 208 Interaction with C1D (By similarity).
 METAL 129 129 Magnesium (By similarity).
 METAL 197 197 Magnesium (By similarity).
 MOD_RES 237 237 Phosphotyrosine (By similarity).  

Keyword

 Complete proteome; Cytoplasm; Developmental protein; Differentiation; DNA-binding; Golgi apparatus; Magnesium; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Spermatogenesis; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 290 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. 

Interpro

 IPR002848; Translin.
 IPR016069; Translin_C.
 IPR016068; Translin_N. 

Pfam

 PF01997; Translin 

SMART

  

PROSITE

  

PRINTS