| Tag | Content |
|---|
| CPLM ID | CPLM-013341 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Elongation of very long chain fatty acids protein 5 |
Protein Synonyms/Alias | 3-keto acyl-CoA synthase ELOVL5; ELOVL fatty acid elongase 5; ELOVL FA elongase 5; Very-long-chain 3-oxoacyl-CoA synthase 5 |
Gene Name | ELOVL5 |
Gene Synonyms/Alias | QflA-11914 |
Created Date | July 27, 2013 |
Organism | Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) |
NCBI Taxa ID | 9541 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 13 | ASLSTYFKALLGPRD | ubiquitination | [1] | | 56 | GPKYMRNKQPFSCRG | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids (By similarity). |
Sequence Annotation | MOD_RES 273 273 Phosphoserine (By similarity).
MOD_RES 281 281 Phosphothreonine (By similarity).
MOD_RES 283 283 Phosphoserine (By similarity).
MOD_RES 285 285 Phosphoserine (By similarity). |
Keyword | Endoplasmic reticulum; Fatty acid biosynthesis; Fatty acid metabolism; Lipid biosynthesis; Lipid metabolism; Membrane; Phosphoprotein; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 299 AA |
Protein Sequence | MEHFDASLST YFKALLGPRD TRVKGWFLLD NYIPTFICSV IYLLIVWLGP KYMRNKQPFS 60
CRGILVVYNL GLTLLSLYMF CELVTGVWEG KYNFFCQGTR TAGESDMKII RVLRWYYFSK 120
LIEFMDTFFF ILRKNNHQIT VLHVYHHASM LNIWWFVMNW VPCGHSYFGA TLNSFIHVLM 180
YSYYGLSSVP SMRPYLWWKK YITQGQLLQF VLTIIQTSCG VIWPCTFPLG WLYFQIGYMI 240
SLIALFTNFY IQTYNKKGAS RRKDHLKDHQ NGSVAAVNGH TNSFSPLENN VKPRKLRKD 299 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0009922; F:fatty acid elongase activity; ISS:UniProtKB. GO:0034625; P:fatty acid elongation, monounsaturated fatty acid; ISS:UniProtKB. GO:0034626; P:fatty acid elongation, polyunsaturated fatty acid; ISS:UniProtKB. GO:0042761; P:very long-chain fatty acid biosynthetic process; ISS:UniProtKB. |
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