CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020515
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Maspardin 
Protein Synonyms/Alias
 Acid cluster protein 33; Spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog 
Gene Name
 Spg21 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
298AEELEVQKGRLGLSQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May play a role as a negative regulatory factor in CD4- dependent T-cell activation (By similarity). 
Sequence Annotation
 MOD_RES 304 304 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 308 AA 
Protein Sequence
MGEIKVSPDY NWFRSTVPLK KIIVDDDDSK IWSLYDAGPR SIRCPLIFLP PVSGTADVFF 60
QQILALTGWG YRVIALQYPV YWDHLEFCDG FRKLLDHLQL DKVHLFGASL GGFLAQKFAE 120
YTHKSPRVHS LILCNAFSDT SIFNQTWTAN SFWLMPAFML KKIVLGNFSS GPVDPMMADA 180
IDFMVDRLES LGQSELASRL TLNCQNSYVE PHKIRDIPVT IMDVFDQSAL STEAKEEMYK 240
LYPNARRAHL KTGGNFPYLC RSAEVNLYVQ IHLLQFHGTK YAAIDPSVVS AEELEVQKGR 300
LGLSQEEP 308 
Gene Ontology
 GO:0005829; C:cytosol; ISS:UniProtKB.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0030140; C:trans-Golgi network transport vesicle; ISS:UniProtKB.
 GO:0042609; F:CD4 receptor binding; ISS:UniProtKB. 
Interpro
 IPR026151; Maspardin. 
Pfam
  
SMART
  
PROSITE
  
PRINTS