UniProt Accession

 D2KFR9_HUMAN; D2KFR9 

Genbank Protein ID

 AC067945; GU211348 

Genbank Nucleotide ID

 ADA59517.1 

Protein Name

 Signal transducer and activator of transcription 1-alpha/beta 

Protein Synonyms/Alias

 Truncated signal transducer and activator of transcription 1 

Gene Name

 STAT1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
114	SCLKEERKILENAQR	ubiquitination	[1]
138	QSTVMLDKQKELDSK	ubiquitination	[1, 2, 3]
152	KVRNVKDKVMCIEHE	ubiquitination	[1]
173	LQDEYDFKCKTLQNR	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 193 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0004871; F:signal transducer activity; IEA:InterPro. 

Interpro

 IPR013800; STAT_TF_alpha.
 IPR015988; STAT_TF_coiled-coil.
 IPR001217; STAT_TF_core.
 IPR013799; STAT_TF_prot_interaction. 

Pfam

 PF01017; STAT_alpha
 PF02865; STAT_int 

SMART

 SM00964; STAT_int 

PROSITE

  

PRINTS