CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001902
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 T-cell receptor beta chain V region YT35 
Protein Synonyms/Alias
  
Gene Name
 TRBV12-3 
Gene Synonyms/Alias
 TCRBV8S1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
43QEVTLRCKPISGHNSubiquitination[1, 2]
87PEDRFSAKMPNASFSubiquitination[1, 2, 3]
97NASFSTLKIQPSEPRubiquitination[1, 2, 3]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
 CARBOHYD 90 90 N-linked (GlcNAc...).  
Keyword
 Complete proteome; Glycoprotein; Immunoglobulin domain; Receptor; Reference proteome; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 135 AA 
Protein Sequence
MDSWTFCCVS LCILVAKHTD AGVIQSPRHE VTEMGQEVTL RCKPISGHNS LFWYRQTMMR 60
GLELLIYFNN NVPIDDSGMP EDRFSAKMPN ASFSTLKIQP SEPRDSAVYF CASSFSTCSA 120
NYGYTFGSGT RLTVV 135 
Gene Ontology
 GO:0005886; C:plasma membrane; NAS:UniProtKB.
 GO:0042287; F:MHC protein binding; NAS:UniProtKB.
 GO:0042605; F:peptide antigen binding; NAS:UniProtKB.
 GO:0006955; P:immune response; NAS:UniProtKB.
 GO:0031295; P:T cell costimulation; TAS:Reactome.
 GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub.
 IPR013106; Ig_V-set. 
Pfam
 PF07686; V-set 
SMART
 SM00409; IG 
PROSITE
 PS50835; IG_LIKE 
PRINTS