UniProt Accession

 D3ZBP2_RAT; D3ZBP2 

Genbank Protein ID

 AABR06054940; AABR06054941; CH473975 

Genbank Nucleotide ID

 EDL95598.1 

Protein Name

 Protein Sin3a 

Protein Synonyms/Alias

 Transcriptional regulator, SIN3A (Yeast) (Predicted) 

Gene Name

 Sin3a 

Gene Synonyms/Alias

 Sin3a_predicted; rCG_57822 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
876	FSNTAAQKLRGMDEV	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 1129 AA 

Protein Sequence

Gene Ontology

 GO:0000785; C:chromatin; IDA:RGD.
 GO:0000776; C:kinetochore; IEA:Compara.
 GO:0043234; C:protein complex; IDA:RGD.
 GO:0016580; C:Sin3 complex; IEA:Compara.
 GO:0005667; C:transcription factor complex; IEA:Compara.
 GO:0017053; C:transcriptional repressor complex; IEA:Compara.
 GO:0003682; F:chromatin binding; IEA:Compara.
 GO:0003677; F:DNA binding; IEA:Compara.
 GO:0032403; F:protein complex binding; IDA:RGD.
 GO:0033558; F:protein deacetylase activity; IEA:Compara.
 GO:0001106; F:RNA polymerase II transcription corepressor activity; IEA:Compara.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0002218; P:activation of innate immune response; IEA:Compara.
 GO:0007568; P:aging; IDA:RGD.
 GO:0034613; P:cellular protein localization; IEA:Compara.
 GO:0071333; P:cellular response to glucose stimulus; IEA:Compara.
 GO:0006260; P:DNA replication; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:1901675; P:negative regulation of histone H3-K27 acetylation; IEA:Compara.
 GO:1900181; P:negative regulation of protein localization to nucleus; IEA:Compara.
 GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IEA:Compara.
 GO:0031937; P:positive regulation of chromatin silencing; IEA:Compara.
 GO:0002230; P:positive regulation of defense response to virus by host; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IDA:RGD.
 GO:0051595; P:response to methylglyoxal; IEA:Compara.
 GO:0010243; P:response to organic nitrogen; IDA:RGD. 

Interpro

 IPR013194; HDAC_interact.
 IPR003822; PAH. 

Pfam

 PF02671; PAH
 PF08295; Sin3_corepress 

SMART

 SM00761; HDAC_interact 

PROSITE

 PS51477; PAH 

PRINTS