CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017580
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein O-glucosyltransferase 1 
Protein Synonyms/Alias
 CAP10-like 46 kDa protein; hCLP46; KTEL motif-containing protein 1; Myelodysplastic syndromes relative protein 
Gene Name
 POGLUT1 
Gene Synonyms/Alias
 C3orf9; CLP46; KTELC1; MDSRP; MDS010; UNQ490/PRO1006 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
238LVDAEYTKNQAWKSMubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 UDP-glucosyltransferase. 
Sequence Annotation
 MOTIF 389 392 Prevents secretion from ER (Potential).
 CARBOHYD 40 40 N-linked (GlcNAc...) (Potential).
 CARBOHYD 53 53 N-linked (GlcNAc...) (Potential).
 CARBOHYD 204 204 N-linked (GlcNAc...) (Potential).
 CARBOHYD 373 373 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Glycoprotein; Glycosyltransferase; Polymorphism; Reference proteome; Signal; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 392 AA 
Protein Sequence
MEWWASSPLR LWLLLFLLPS AQGRQKESGS KWKVFIDQIN RSLENYEPCS SQNCSCYHGV 60
IEEDLTPFRG GISRKMMAEV VRRKLGTHYQ ITKNRLYREN DCMFPSRCSG VEHFILEVIG 120
RLPDMEMVIN VRDYPQVPKW MEPAIPVFSF SKTSEYHDIM YPAWTFWEGG PAVWPIYPTG 180
LGRWDLFRED LVRSAAQWPW KKKNSTAYFR GSRTSPERDP LILLSRKNPK LVDAEYTKNQ 240
AWKSMKDTLG KPAAKDVHLV DHCKYKYLFN FRGVAASFRF KHLFLCGSLV FHVGDEWLEF 300
FYPQLKPWVH YIPVKTDLSN VQELLQFVKA NDDVAQEIAE RGSQFIRNHL QMDDITCYWE 360
NLLSEYSKFL SYNVTRRKGY DQIIPKMLKT EL 392 
Gene Ontology
 GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.
 GO:0035251; F:UDP-glucosyltransferase activity; IDA:UniProtKB.
 GO:0035252; F:UDP-xylosyltransferase activity; IEA:Compara.
 GO:0072358; P:cardiovascular system development; IEA:Compara.
 GO:0007219; P:Notch signaling pathway; TAS:Reactome.
 GO:0006493; P:protein O-linked glycosylation; IDA:MGI.
 GO:0008593; P:regulation of Notch signaling pathway; IEA:Compara. 
Interpro
 IPR006598; LipoPS_modifying. 
Pfam
 PF05686; Glyco_transf_90 
SMART
 SM00672; CAP10 
PROSITE
 PS00014; ER_TARGET 
PRINTS