CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039416
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Chloride intracellular channel protein 6 
Protein Synonyms/Alias
  
Gene Name
 Clic6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
446EVKTDVNKIEEFLEEacetylation[1]
486AKFSAFIKNTKKDANacetylation[1]
489SAFIKNTKKDANDIYacetylation[1]
498DANDIYEKNLLRALKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 608 AA 
Protein Sequence
TEPKEVSSGS QGQPEGAVIE GPGEPGAADL EGREASEGAA EAPRDLGEGA EAMASGKEEG 60
GCGQDGEIGE VQAQDPRPGP GTETPGTSGA PGEAEAAECD SEGALIPQSG GGAKRQQVQG 120
TSSGLDAQGE APEVPEDARR EPEDPKASEA GEEAESGQEA LGGSAPESQI NPEVQGPVGD 180
NMDTEAPAGE PQGSEGEPQG GGESSPQPQD EAIEIAAAEV GGHEPGELAG ASAADAKGEG 240
ETLRKDGFEE AAPEEARVDS GENGFEEAAP EEARVDSGEN RDQGRLQEET GEEEARPESG 300
LKGPCEEAIQ EKAPDGSLDG EEAKSTGHEE SQVELSNHLA EETSAQGGEE LGRVNGRREN 360
GPASEEGDLG QEHDITLFVK AGSDGESIGN CPFSQRLFMI LWLKGVIFNV TTVDLKRKPA 420
DLQNLAPGTN PPFMTFDGEV KTDVNKIEEF LEEKLVPPRY PKLGTQHPES NSAGNDVFAK 480
FSAFIKNTKK DANDIYEKNL LRALKKLDSY LNSPLPDEID AYSTEDVTVS QRKFLDGDEL 540
TLADCNLLPK LHIIKIVAKK YRGFEFPSEM TGIWRYLNNA YARDEFTNTC PADQEIEHAY 600
SDAAKRMK 608 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro. 
Interpro
 IPR010987; Glutathione-S-Trfase_C-like.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR002946; Int_Cl_channel.
 IPR012336; Thioredoxin-like_fold. 
Pfam
  
SMART
  
PROSITE
 PS50405; GST_CTER 
PRINTS
 PR01263; INTCLCHANNEL.