Tag | Content |
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CPLM ID | CPLM-012720 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 |
Protein Synonyms/Alias | Complex I subunit B13; Complex I-13kD-B; CI-13kD-B; NADH-ubiquinone oxidoreductase 13 kDa-B subunit |
Gene Name | NDUFA5 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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30 | RLRILYTKILDVLEE | acetylation | [1] | 60 | NEKLAMVKAEPDVKK | acetylation | [1] |
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Reference | [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M. Science. 2009 Aug 14;325(5942):834-40. [ PMID: 19608861] |
Functional Description | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Sequence Annotation | MOD_RES 2 2 N-acetylalanine (By similarity). MOD_RES 30 30 N6-acetyllysine. MOD_RES 46 46 N6-acetyllysine (By similarity). MOD_RES 60 60 N6-acetyllysine. MOD_RES 98 98 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Complete proteome; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Respiratory chain; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 116 AA |
Protein Sequence | MAGVLKKTTG LVGLAVCNTP HERLRILYTK ILDVLEEIPK NAAYRKYTEQ ITNEKLAMVK 60 AEPDVKKLED QLQGGQLEEV ILQAEHELNL ARKMREWKLW EPLVEEPPAD QWKWPI 116 |
Gene Ontology | GO:0005747; C:mitochondrial respiratory chain complex I; IDA:UniProtKB. GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB. GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB. GO:0044281; P:small molecule metabolic process; TAS:Reactome. |
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