CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016543
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 IQ calmodulin-binding motif-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 Iqcb1 
Gene Synonyms/Alias
 Kiaa0036 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
558QAHLTTLKHIQAPWWacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 Involved in ciliogenesis. 
Sequence Annotation
 DOMAIN 294 317 IQ 1.
 DOMAIN 318 338 IQ 2.
 DOMAIN 387 416 IQ 3.
 DOMAIN 417 437 IQ 4.  
Keyword
 Alternative splicing; Calmodulin-binding; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 598 AA 
Protein Sequence
MKPAGTDPRI LSLAAEVAKS PEQNVPVILL KLKEIINNTP LGSSELKKVK QDIYCYDLIQ 60
YCLLVLSQDS SRIQGGWSTI SQLTQILSHC CVGLEPGEDG EEFYKELLPS AAENFLILGR 120
RLQTCFINAT KGEEQDKLLH FFQIVTDSLF WLLGGHVQLI QNVLQSDHFL HLLQTDNVQI 180
GASVMTLLQN ILQINSGNLL KIEGKALHSI LDEILFKLLS TPSPVIRSTA TKLLLVLAES 240
HQEILILLRL SACYKGLRSL LNKQETLTEF SRELRQLVDL LTPKIHQEVE EQKLHKAACL 300
IQAYWKGFQT RKRLKKLPSA VIALQRSFRS KRTKMMLELN RQKEEEDLRL KLQLQRQRAM 360
RLSRESRLNM LEIIHPGQVE KYNREMEEKS ALTIQKHWRG YRERKNFRQQ RPSLTEYKAA 420
VTLQRAVLKF LAKCRKKKKL FASWHGLQEL TDARRVELKQ QVDDYVKRHP CSQMSEAASR 480
ELHAQAQERL QHYFMGRAIE ERAQQHREAL MAQISTNIEQ LMKAPSLKEA EGKEPEQFLS 540
RSRPVAAKAK QAHLTTLKHI QAPWWKKLGE EPGDEVDVPK DELSIDLGML FIGGTKPP 598 
Gene Ontology
 GO:0005813; C:centrosome; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0032391; C:photoreceptor connecting cilium; IDA:HGNC.
 GO:0001750; C:photoreceptor outer segment; IDA:HGNC.
 GO:0005516; F:calmodulin binding; ISS:HGNC.
 GO:0042384; P:cilium assembly; IMP:UniProtKB.
 GO:0048496; P:maintenance of organ identity; ISS:HGNC.
 GO:0045494; P:photoreceptor cell maintenance; ISS:HGNC. 
Interpro
 IPR016024; ARM-type_fold.
 IPR000048; IQ_motif_EF-hand-BS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00612; IQ 
SMART
 SM00015; IQ 
PROSITE
 PS50096; IQ 
PRINTS