CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013824
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Spindlin-1 
Protein Synonyms/Alias
  
Gene Name
 SPIN1 
Gene Synonyms/Alias
 SPIN 
Created Date
 July 27, 2013 
Organism
 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) 
NCBI Taxa ID
 9601 
Lysine Modification
Position
Peptide
Type
References
44RSSVGPSKPVSQPRRubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965
Functional Description
 May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity). 
Sequence Annotation
 REGION 53 116 Tudor-like domain 1 (By similarity).
 REGION 132 193 Tudor-like domain 2 (By similarity).
 REGION 213 262 Tudor-like domain 3 (By similarity).
 MOD_RES 124 124 Phosphoserine (By similarity).
 MOD_RES 199 199 Phosphoserine (By similarity).  
Keyword
 Cell cycle; Complete proteome; Developmental protein; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 262 AA 
Protein Sequence
MKTPFGKTPG QRSRADAGHA GVSANMMKKR TSHKKHRSSV GPSKPVSQPR RNIVGCRIQH 60
GWKEGNGPVT QWKGTVLDQV PVNPSLYLIK YDGFDCVYGL ELNKDERVSA LEVLPDRVAT 120
SRISDAHLAD TMIGKAVEHM FETEDGSKDE WRGMVLARAP VMNTWFYITY EKDPVLYMYQ 180
LLDDYKEGDL RIMPDSNDSP PAEREPGEVV DSLVGKQVEY AKEDGSKRTG MVIHQVEAKP 240
SVYFIKFDDD FHIYVYDLVK TS 262 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005819; C:spindle; IEA:Compara.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0007276; P:gamete generation; IEA:InterPro.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. 
Interpro
 IPR003671; Spin_Ssty. 
Pfam
 PF02513; Spin-Ssty 
SMART
  
PROSITE
  
PRINTS