| Tag | Content |
|---|
| CPLM ID | CPLM-017433 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | MPN domain-containing protein |
Protein Synonyms/Alias | |
Gene Name | MPND |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 421 | QEHTYLDKLKISLAS | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Probable protease (By similarity). |
Sequence Annotation | DOMAIN 267 375 MPN.
MOTIF 349 362 JAMM motif.
MOD_RES 2 2 N-acetylalanine.
MOD_RES 8 8 Phosphoserine.
MOD_RES 178 178 Phosphoserine.
MOD_RES 181 181 Phosphoserine. |
Keyword | Acetylation; Alternative splicing; Complete proteome; Hydrolase; Phosphoprotein; Protease; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 471 AA |
Protein Sequence | MAAPEPLSPA GGAGEEAPEE DEDEAEAEDP ERPNAGAGGG RSGGGGSSVS GGGGGGGAGA 60
GGCGGPGGAL TRRAVTLRVL LKDALLEPGA GVLSIYYLGK KFLGDLQPDG RIMWQETGQT 120
FNSPSAWATH CKKLVNPAKK SGCGWASVKY KGQKLDKYKA TWLRLHQLHT PATAADESPA 180
SEGEEEELLM EEEEEDVLAG VSAEDKSRRP LGKSPSEPAH PEATTPGKRV DSKIRVPVRY 240
CMLGSRDLAR NPHTLVEVTS FAAINKFQPF NVAVSSNVLF LLIYQSLFLR GLSLVGWYHS 300
HPHSPALPSL QDIDAQMDYQ LRLQGSSNGF QPCLALLCSP YYSGNPGPES KISPFWVMPP 360
PEQRPSDYGI PMDVEMAYVQ DSFLTNDILH EMMLLVEFYK GSPDLVRLQE PWSQEHTYLD 420
KLKISLASRT PKDQSLCHVL EQVCGVLKQG S 451 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |