CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044033
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Acyl-coenzyme A thioesterase 9, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 ACOT9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
13TNWRDHVKAMEERKLubiquitination[1]
137VARDSENKGPAFVNPubiquitination[2, 3, 4]
176FSSTSLLKMAPSAEEubiquitination[1, 4]
198FLSTLDPKTISFRSRacetylation[5]
198FLSTLDPKTISFRSRubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [5] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 264 AA 
Protein Sequence
IVGASTNWRD HVKAMEERKL LHSFLAKSQD GLPPRRMKDS YIEVLLPLGS EPELREKYLT 60
VQNTVRFGRI LEDLDSLGDM CKKSLSPEQD IKFSGHVSWV GKTSMEVKMQ MFQLHGDEFC 120
PVLDATFVMV ARDSENKGPA FVNPLIPESP EEEELFRQGE LNKGRRIAFS STSLLKMAPS 180
AEERTTIHEM FLSTLDPKTI SFRSRVLPSN AVWMENSKLK SLEICHPQER NIFNRIFGGF 240
LMRKAYELAW ATACSFGGSR PFVV 264 
Gene Ontology
  
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS