UniProt Accession

 NUOI2_RHOPA; Q6N1Z5 

Genbank Protein ID

 BX572606 

Genbank Nucleotide ID

 CAE29698.1 

Protein Name

 NADH-quinone oxidoreductase subunit I 2 

Protein Synonyms/Alias

 NADH dehydrogenase I subunit I 2; NDH-1 subunit I 2 

Gene Name

 nuoI2 

Gene Synonyms/Alias

 RPA4257 

Created Date

 July 27, 2013 

Organism

 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 

NCBI Taxa ID

 258594 

Lysine Modification

Position	Peptide	Type	References
137	LLISGEGKVRGYRYW	acetylation	[1]

Reference

 [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.
 Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC.
 J Biol Chem. 2012 May 4;287(19):15590-601. [PMID: 22416131] 

Functional Description

 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). 

Sequence Annotation

 DOMAIN 41 73 4Fe-4S ferredoxin-type 1.
 DOMAIN 83 112 4Fe-4S ferredoxin-type 2.
 METAL 53 53 Iron-sulfur 1 (4Fe-4S) (By similarity).
 METAL 56 56 Iron-sulfur 1 (4Fe-4S) (By similarity).
 METAL 59 59 Iron-sulfur 1 (4Fe-4S) (By similarity).
 METAL 63 63 Iron-sulfur 2 (4Fe-4S) (By similarity).
 METAL 92 92 Iron-sulfur 2 (4Fe-4S) (By similarity).
 METAL 95 95 Iron-sulfur 2 (4Fe-4S) (By similarity).
 METAL 98 98 Iron-sulfur 2 (4Fe-4S) (By similarity).
 METAL 102 102 Iron-sulfur 1 (4Fe-4S) (By similarity).  

Keyword

 4Fe-4S; Cell inner membrane; Cell membrane; Complete proteome; Iron; Iron-sulfur; Membrane; Metal-binding; NAD; Oxidoreductase; Quinone; Repeat; Ubiquinone. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 173 AA 

Protein Sequence

Gene Ontology

 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:HAMAP.
 GO:0050136; F:NADH dehydrogenase (quinone) activity; IEA:HAMAP.
 GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
 GO:0019684; P:photosynthesis, light reaction; IEA:HAMAP. 

Interpro

 IPR001450; 4Fe4S-bd_dom.
 IPR017896; 4Fe4S_Fe-S-bd.
 IPR017900; 4Fe4S_Fe_S_CS.
 IPR010226; NADH_quinone_OxRdtase_chainI. 

Pfam

 PF12838; Fer4_7 

SMART

  

PROSITE

 PS00198; 4FE4S_FER_1
 PS51379; 4FE4S_FER_2 

PRINTS