CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036012
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Tumor suppressor candidate 3 
Protein Synonyms/Alias
  
Gene Name
 TUSC3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
180FAAEQLAKWIADRTDubiquitination[1, 2]
Reference
 [1] A data set of human endogenous protein ubiquitination sites.
 Shi Y, Chan DW, Jung SY, Malovannaya A, Wang Y, Qin J.
 Mol Cell Proteomics. 2011 May;10(5):M110.002089. [PMID: 20972266]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 289 AA 
Protein Sequence
MGARGAPSRR RQAGRRLRYL PTGSFPFLLL LLLLCIQLGG GQKKKENLLA EKVEQLMEWS 60
SRRSIFRMNG DKFRKFIKAP PRNYSMIVMF TALQPQRQCS VCRQANEEYQ ILANSWRYSS 120
AFCNKLFFSM VDYDEGTDVF QQLNMNSAPT FMHFPPKGRP KRADTFDLQR IGFAAEQLAK 180
WIADRTDVHI RVFRPPNYSG TIALALLVSL VGGLLYLRRN NLEFIYNKTG WAMVSLCIVF 240
AMTSGQMWNH IRGPPYAHKN PHNGQVSYIH GSSQAQFVAE SHIILVLTS 289 
Gene Ontology
 GO:0045454; P:cell redox homeostasis; IEA:InterPro. 
Interpro
 IPR006844; Mg_transporter-1.
 IPR021149; OligosaccharylTrfase_OST3/OST6.
 IPR012336; Thioredoxin-like_fold.
 IPR013766; Thioredoxin_domain. 
Pfam
 PF04756; OST3_OST6
 PF00085; Thioredoxin 
SMART
  
PROSITE
  
PRINTS